Post-review changes

Requests for changes to core services and/or an increase in the number of subjects must be reviewed and approved prior to implementation at the CRC.

Most of these can be handled administratively, however significant changes to the scientific design of the study may necessitate another review by the CRCN Scientific Review Committee. This requires a Modification Memorandum and the resubmission of the study application with appropriate sections revised indicating the changes (highlighted). If applicable, documentation of IRB approval of these changes will also be required.

The Modification Memorandum and application must be submitted by the Friday before the regularly scheduled CRCN Scientific Review Committee meeting (i.e. first Thursday of the month for Children’s, third Thursday of the month for the UW).

Please address the Modification Memorandum to the CRCN Review Committee Chair and the ITHS Administrative Director and email to ithsapps@u.washington.edu.