CEEH Facility Core #1: Functional Genomics & Proteomics

Description

The Functional Genomics and Proteomics Lab provides state-of-the-art genomics and proteomics based technologies that can be used to investigate gene-environment interactions in the context of basic environmental health sciences research and population-based studies.  The Functional Genomics and Proteomics Laboratory is a shared resource that allows CEEH investigators access to the latest technology and enables them to perform cutting-edge research.

The core provides:

  • Access to advanced nucleic acids diagnostics instrumentation center with multi-user access to automated Sanger DNA sequencing, genotyping/haplotyping services, gene expression profiling (mRNA and microRNA), TaqMan based quantitative gene expression analysis, and other DNA and RNA-based analytical technologies.
  • Technical support and pipeline access Next Generation Sequencing capabilities that allow a number of applications, including targeted re-sequencing for genotyping analysis, Chromatin Immunoprecipitation based sequencing, transcriptome sequencing, and methylation analysis.
  • Custom specialized microarray platforms (e.g. microarray-based genomic enrichment, microRNA arrays)
  • Access to state-of-the-art proteomic instrumentation for automated protein identification, and other protein-based analytical methodologies.
  • Consultation on meaningful integration of genomic, proteomic and metabolomic approaches to individual research projects.
  • Collaboration BioInformatics and Biostatistics Services Core to facilitate efficient study design and overall coordination of a project, including validation of data that has been analyzed by Bioinformatics and Biostatistics Core
  • Access to the TaqMan OpenArray Genotyping System that will allow investigators to perform faster and more cost-effective high-sample-throughput genotyping studies
Category of resources
  • Microarray/Molecular Biology (DNA, RNA or protein sequencing/synthesis, genotyping, PCR, gene arrays, etc.)
  • Biological Macromolecule Analysis (proteomics, x-ray crystallography, NMR spectroscopy, etc).
Services provided
  • Access to technology services (i.e. microarray, specimen analysis)
  • Consultations (i.e. study design, experiment design)
  • Professional service (i.e. analysis, report writing, manuscript review)
Specialty equipment/services
Web address(es) CEEH Facility Core #1: Functional Genomics & Proteomics
Location Washington - University of Washington -Main Campus
4225 Roosevelt Way N.E., Suite 100
Manager or contact Fred Farin
Users who may access
This listing was last modified on December 15, 2009.

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