{"id":300,"date":"2015-05-13T14:36:37","date_gmt":"2015-05-13T21:36:37","guid":{"rendered":"http:\/\/www.iths.org\/v4-stage\/?page_id=92"},"modified":"2023-09-07T15:16:59","modified_gmt":"2023-09-07T22:16:59","slug":"correlative-studies","status":"publish","type":"page","link":"https:\/\/www.iths.org\/cpci\/activities\/correlative-studies\/","title":{"rendered":"Correlative Studies"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text]<\/p>\n<h2>Enhancing rigorous assessment of key biologic correlates uniquely associated with cellular immunotherapy mechanisms of action in conjunction with safety and outcome measures.<\/h2>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text]Novel therapeutic modalities such as cellular immunotherapies require advanced correlative assay platforms not available in hospital-based clinical laboratories that reliably and reproducibly benchmark mechanisms of actions and predict correlatives of safety and efficacy.<\/p>\n<p>The Correlative Working Group has collaborated on best practices for developing reproducible sample collection and process standards for use across Consortium trials. We are also leveraging a web-based data platform for the integration, analysis and visualization and sharing of data across the Consortium. In addition to collecting trial data, this system will enable the creation of a virtual biobank where specimens can be shared across the Consortium. \u00a0Finally, we are establishing outcome measures to assess safety and efficacy and promote the rapid translation of findings into future products.[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h3>Related Papers<\/h3>\n<p><a class=\"prettylink pdf\"  href=\"https:\/\/www.iths.org\/cpci\/wp-content\/uploads\/sites\/35\/2023\/09\/Current-Oncology-Reports_CNS_20230404.pdf\"><span style=\"float:right\"><\/span>\u201cCurrent Oncology Reports Publication: Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data<\/a><a class=\"prettylink pdf\"  href=\"https:\/\/www.iths.org\/cpci\/wp-content\/uploads\/sites\/35\/2022\/01\/CPCI_Correlative-Working-Group_Cytotherapy-Paper_Published-Online_20211026.pdf\"><span style=\"float:right\"><\/span>Cytotherapy Publication: Alignment of practices for data harmonization across multi-center cell therapy trials: a report from the Consortium for Pediatric Cellular Immunotherapy<\/a>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Participate in individual collaborative consults where collaborative members are engaged in in-progress consult discussions.<\/p>\n","protected":false},"author":2,"featured_media":945,"parent":55,"menu_order":30,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-300","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/pages\/300","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/comments?post=300"}],"version-history":[{"count":13,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/pages\/300\/revisions"}],"predecessor-version":[{"id":1181,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/pages\/300\/revisions\/1181"}],"up":[{"embeddable":true,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/pages\/55"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/media\/945"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/cpci\/wp-json\/wp\/v2\/media?parent=300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}