06 Jan Brain Activation and Satiety in Children 2 (BASIC2) Study
BASIC2 is studying ways to help overweight kids and their parents reach and maintain a healthy weight. This longitudinal study is trying to learn if the study medicine combined with family-based treatment helps kids better manage their weight.
You and your child would attend free family-based weight management classes, which are about 90 minutes long and meet once a week for 6 months at a Seattle Children’s Clinic site, or remotely.
Your child would be randomized to receive either a study medicine that would help them with weight control OR a placebo medicine.
Your child would have 6 study visits spread out over 21 months. Three 4 hour visits at the University of Washington, where your child will have two MRI scans, blood testing, body measurements and surveys to complete. Three 60 minute visits at Seattle Children’s for body measurements at 2, 6 and 12 months after treatment ends.
Children who take part in this study would receive up to $480 in gift cards and checks.
Age 10-12 years old
BMI ≥ 95th percentile for age and sex
Able to have an MRI
Willingness to engage in family-based weight management treatment and to receive once weekly injections
Ability and willingness to participant in study visits including MRI scans and blood draws.
No severe food allergies
No major medical conditions
No history of or current eating disorder
Not currently taking weight loss medications
Not currently enrolled in a weight loss program
Not taking medications known to alter appetite or metabolism
Additional Study Details
Full Study Title
Brain Systems and Behaviors Underlying Response to Obesity Treatment in Children
Christian Roth, MD
Brian Saelens, PhD
Ellen Schur, MD, MS
Accepts Healthy Volunteers?
SEATTLE CHILDREN’S RESEARCH INSTITUTE-BUILDING CURE
1920 Terry Ave
Seattle, Washington 98101
UNIVERSITY OF WASHINGTON MEDICAL CENTER
1959 NE Pacific St.
Seattle Washington 98195