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Brain Inflammation and Glucose Regulation (BIGR)

Brain Inflammation and Glucose Regulation (BIGR)

In research done in animals, scientists have discovered that certain diets, especially those high in fat, cause not only weight gain but changes in the brain. These changes occur in the area of the brain that regulates body weight and fat stores as well as glucose levels. This region is called the hypothalamus.

The purpose of the study is to learn more about the differences in human brain structure in people with and without diabetes and if these differences affect regulation of blood sugar over time. Participants will be asked to complete study visits at the University of Washington Medical Center.

Participant Eligibility

  • Age 25-60
  • Currently Overweight or Obese
  • Diagnosed with Type 2 Diabetes
  • Available to come to UW Medical Center and UW South Lake Union 2-3 Times
  • Not Taking Insulin
  • Non-Smoker
  • No History of Bariatric Surgery


Roz De Leon
(206) 616-6360

Additional Study Details

Full Study Title
Brain Inflammation and Glucose Regulation

Study ID: 00003318
Start Date: 12/1/2017
End Date: 11/29/2019

Ellen Schur, MD, MS

Accepts Healthy Volunteers?

Study Site(s)

1959 NE Pacific St
Seattle, Washington 98195
United States
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750 Republican St
Seattle, Washington 98109
United States
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Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.