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Conquer the Common Cold

Conquer the Common Cold

The goal of this study is to enroll 200 healthy participants who will be collecting nasal swabs over a period of 1 year. 100 participants will be enrolled in each of two categories based on self-report over the last 3 years; susceptible (≥ 4 colds per year) or resistant (≤2 colds per year). Nasal swabs will be self-collected monthly as well as at the onset of any cold symptoms and mailed back to the site. There will be two in-person study visits at enrollment and end of study. At these visits, participants will also undergo a blood draw and additional nasal swab and optional stool swab for microbiome. At the time of each swab collection, participants will complete a corresponding online survey via REDCap. Participants will receive monetary compensation for these visits as well as each swab that is collected.

Participant Eligibility

Inclusion Criteria:
• Age: 18 to 60 years at time of enrollment
• Weight:  110lbs.
• Ability and willingness to provide informed consent
• Close contact with children through living arrangements or employment as defined by one of the following:
o Parent, guardian, or adult residing in a household who have direct regular contact (at least 3 days/week on average) to children age 0-6 that attend daycare or kindergarten at least 3 times a week
o Employee of childcare facility with direct contact to children ages 0-6
o Employee of pediatric care facility with direct contact to children ages 0-6
o Employee with direct contact to special needs children ages 0-18
• Good general health as shown by medical history
• Self-reported history of  4 colds per year OR ≤ 1 cold per year
• Venous access sufficient to allow for the protocol-required blood draws.
Exclusion Criteria:
• Known HIV Positive
• Known immunodeficiency
• Glucocorticoids or other immunosuppressive medications taken within the prior 6 months. Not excluded: topical corticosteroids or a single course of systemic corticosteroids
• Known pregnancy

Contact

Conquer the Common Cold Study Team
(206) 667-2060

Additional Study Details

Full Study Title
T-cell responses to conserved regions of human Rhinoviruses (HRV) are associated with protection from the common cold.

Study ID: FH8353
Start Date: 04/03/2019
End Date: 04/03/2020

Investigator(s)
Michael Boeckh

Accepts Healthy Volunteers?
Yes

Study Site(s)

Fred Hutchinson Cancer Research Center

1100 Fairview Ave N. Prevention Center
Seattle, Washington 98109



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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