Quick Links

Conquer the Common Cold

Conquer the Common Cold

The goal of this study is to enroll 200 healthy participants who will be collecting nasal swabs over a period of 1 year. 100 participants will be enrolled in each of two categories based on self-report over the last 3 years; susceptible (≥ 4 colds per year) or resistant (≤2 colds per year). Nasal swabs will be self-collected monthly as well as at the onset of any cold symptoms and mailed back to the site. There will be two in-person study visits at enrollment and end of study. At these visits, participants will also undergo a blood draw and additional nasal swab and optional stool swab for microbiome. At the time of each swab collection, participants will complete a corresponding online survey via REDCap. Participants will receive monetary compensation for these visits as well as each swab that is collected.

Participant Eligibility

Inclusion Criteria:
• Age: 18 to 60 years at time of enrollment
• Weight:  110lbs.
• Ability and willingness to provide informed consent
• Close contact with children through living arrangements or employment as defined by one of the following:
o Parent, guardian, or adult residing in a household who have direct regular contact (at least 3 days/week on average) to children age 0-6 that attend daycare or kindergarten at least 3 times a week
o Employee of childcare facility with direct contact to children ages 0-6
o Employee of pediatric care facility with direct contact to children ages 0-6
o Employee with direct contact to special needs children ages 0-18
• Good general health as shown by medical history
• Self-reported history of  4 colds per year OR ≤ 1 cold per year
• Venous access sufficient to allow for the protocol-required blood draws.
Exclusion Criteria:
• Known HIV Positive
• Known immunodeficiency
• Glucocorticoids or other immunosuppressive medications taken within the prior 6 months. Not excluded: topical corticosteroids or a single course of systemic corticosteroids
• Known pregnancy


Conquer the Common Cold Study Team
(206) 667-2060

Additional Study Details

Full Study Title
T-cell responses to conserved regions of human Rhinoviruses (HRV) are associated with protection from the common cold.

Study ID: FH8353
Start Date: 04/03/2019
End Date: 04/03/2020

Michael Boeckh

Accepts Healthy Volunteers?

Study Site(s)

Fred Hutchinson Cancer Research Center

1100 Fairview Ave N. Prevention Center
Seattle, Washington 98109


Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.