Quick Links

EFFECT OF TESTOSTERONE TREATMENT ON DRUG METABOLISM AND TRANSPORT

EFFECT OF TESTOSTERONE TREATMENT ON DRUG METABOLISM AND TRANSPORT

Your gender-affirming hormone therapy contains testosterone, a hormone that your body creates and uses naturally. Testosterone is prepared as a medication that you can take to increase your hormone levels. Changes in testosterone levels in your body may affect how your body processes certain medicines. The purpose of this study is to find out how testosterone therapy affects a single tracer dose of approved medicines in your blood (midazolam, digoxin, and acetaminophen) and to confirm testosterone treatment does not affect natural bacterial in your gut.

Participant Eligibility

Inclusion Criteria:
1) Self-identified trans* adult at least 18 years of age.
2) Not taking testosterone treatment currently.
3) Planning to start testosterone treatment through care provider for gender-affirming medical care.

Exclusion Criteria:
1) Unwilling/unable to return for project follow-up visits.
2) Unwilling/unable to provide written informed consent.

Contact

Lauren Cirrincione
(650) 353-7782

Additional Study Details

Full Study Title
EFFECT OF TESTOSTERONE TREATMENT ON DRUG METABOLISM AND TRANSPORT

Study ID: STUDY00011644
Start Date: 04/30/2021
End Date: 06/30/2022

Investigator(s)
Lauren Cirrincione, PharmD (she/her)

Accepts Healthy Volunteers?
Yes

Study Site(s)

University of Washington

1959 NE Pacific St
Seattle, Washington 98195



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

SITE PARTNERS
uw-footer