09 Feb EFFECT OF TESTOSTERONE TREATMENT ON DRUG METABOLISM AND TRANSPORT
Your gender-affirming hormone therapy contains testosterone, a hormone that your body creates and uses naturally. Testosterone is prepared as a medication that you can take to increase your hormone levels. Changes in testosterone levels in your body may affect how your body processes certain medicines. The purpose of this study is to find out how testosterone therapy affects a single tracer dose of approved medicines in your blood (midazolam, digoxin, and acetaminophen) and to confirm testosterone treatment does not affect natural bacterial in your gut.
Participant Eligibility
Inclusion Criteria:
1) Self-identified trans* adult at least 18 years of age.
2) Not taking testosterone treatment currently.
3) Planning to start testosterone treatment through care provider for gender-affirming medical care.
Exclusion Criteria:
1) Unwilling/unable to return for project follow-up visits.
2) Unwilling/unable to provide written informed consent.
Contact
Lauren Cirrincione
(650) 353-7782
Additional Study Details
Full Study Title
EFFECT OF TESTOSTERONE TREATMENT ON DRUG METABOLISM AND TRANSPORT
Investigator(s)
Lauren Cirrincione, PharmD (she/her)
Accepts Healthy Volunteers?
Yes
Study Site(s)
University of Washington
1959 NE Pacific St
Seattle, Washington 98195