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Impact of Probiotics on Drug, Vitamin, and Hormone Metabolism

Impact of Probiotics on Drug, Vitamin, and Hormone Metabolism

The purpose of this study is to find out if a probiotics supplement called Visbiome will speed up or slow down how quickly the intestine and liver break down some medications, vitamins and hormones. On two 13-hour study days, the participant will be given an intravenous and oral dose of midazolam and an oral dose acetaminophen. A stool sample and multiple blood and urine samples will be collected. In between the two drug study days, the participant will be given the probiotics supplement for 28 days. The participant will earn $500 for your participation.

Participant Eligibility

– Male between 18 – 40 yrs old.
– A healthy weight for your height (BMI 18.5-25 kg/m²).
– Agree to abstain from grapefruit and grapefruit products during the study.
– A non-smoker.
– NOT taking prescription medications.
– NOT lactose intolerant and NOT allergic to milk.
– NOT have a history of liver, kidney, gastrointestinal or heart disease.
– NOT participated in a clinical study in the past 30 days.

Contact

Brice Thompson
(206) 685-8718

Additional Study Details

Full Study Title
Impact of Probiotics on Drug, Vitamin, and Hormone Metabolism

Study ID: STUDY00007095
Start Date: 07/30/2019
End Date: 07/29/2020

Investigator(s)
Yvonne Lin
Brice Thompson
Freddy Chen

Accepts Healthy Volunteers?
Yes

Study Site(s)

University of Washington Medical Center

1959 NE Pacific Translational Research Unit
Seattle, Washington 98195



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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