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Kidney Stone Smart Water Bottle Study

Kidney Stone Smart Water Bottle Study


The Prevention of Urinary Stones with Hydration (PUSH) is a two arm randomized controlled trial of adaptable behavioral interventions to increase fluid intake, and remote monitoring of fluid intake through a “smart” water bottle. The study follow-up period is 24 months. Participants in the intervention arm will receive an individualized “fluid prescription”, financial incentives for meeting daily fluid goals, and coaching to overcome fluid intake barriers. Control arm participants will also receive a smart water bottle, and will be informed about the urine output recommended by the AUA. The only in-person visits for PUSH are at the beginning and the end of the study for a low dose CT or ultrasound. All other contacts are remote. There are 24-hour urine home collections done at several points throughout the follow-up period.

Participant Eligibility

Inclusion Criteria:
– At least 12 years old
– You or your child has had at least 1 symptomatic stone event (passage or procedural intervention) within 3 years prior to enrollment
– Low 24-hour urine volume (if known)
– You own and are willing to use (or, if your child will participate in the study, your child uses) a smartphone or other device (e.g. tablet) compatible with the study-provided wireless “smart” water bottle

Exclusion Criteria:
– Spinal cord injury
– Currently undergoing active treatment for cancer except basal cell skin cancer, or patients with a history of cancer who completed their initial therapy < 1 year before screening.
– Study participants with comorbidities that preclude high fluid intake or prior surgery precluding high fluid intake or leading to GI fluid losses
– History of or current Crohn’s disease, ulcerative colitis, short gut syndrome (e.g. ileostomy, bowel bypass surgery to treat obesity, small bowel resection), chronic diarrhea, or GI tract ostomy.
– History of malabsorptive (e.g., Roux-en-Y gastric bypass) or restrictive (e.g., sleeve gastrectomy) bariatric surgery procedures
– Congestive heart failure
– Lung disease with a home oxygen requirement
– Cirrhosis with ascites
– Renal transplant recipient
– Bedridden study participants


Holly Covert
(206) 616-5170

Additional Study Details

Full Study Title
Prevention of Urinary Stones with Hydration

Study ID: STUDY00002460
Start Date: 08/18/2017
End Date: 08/01/2020

Jonathan Harper, MD
Hunter Wessells, MD
Jonathan Ellison, MD

Accepts Healthy Volunteers?

Study Site(s)

Northwest Kidney Stone Center

1536 N. 115th St. Suite 300
Seattle, Washington 98133

Seattle Children’s Hospital

4800 Sand Point Way NE
Seattle Washington 98105


Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.