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Symptoms of Lower Urinary Tract Dysfunction

Symptoms of Lower Urinary Tract Dysfunction

We are enrolling healthy control subjects with NO urinary dysfunction. The purpose of this study is to improve our understanding of lower urinary tract symptoms (LUTS) and to learn more about people’s experiences, along with how to measure different aspects of people with LUTS experiences.

Study participation includes:
• Eligibility assessment and LUTS tool (1- month recall)
• One in-person visit (UWMC-Montlake) that is expected to last up to 2 hours
• Collection of Demographics, general health and urinary history
• Physical exam, Post-Urine Residual Urine Volume (PVR), clinic
testing (urine analysis, labs)
• Completing Online Self- Reported Measures questionnaires
• Completing voiding/intake and food diaries, either online or on paper
• Biosample collection (blood, urine, and dry blood spots)

You will be compensated $125.00.00 for your completed participation. You will also receive a free parking voucher for the UWMC Triangle parking garage to cover parking costs while at your study visit.

Along with the main study (Project A), there are four sub-studies. Once you consent to participate in Project A, you may participate in any or all of the sub-studies that you are eligible for.
The sub-studies include:
* Project B: A central sensitization study that looks at participants’ intensity of
sensations
* Project C: A physical activity and sleep study that uses a monitor to collect
your data
* (For women only) Project D: A organ-based study to better understand how the
urethra interacts with the bladder and how it affects LUTS in women.

Participant Eligibility

Men and women, age 60 – 80 with healthy bladders and no symptoms of bladder urgency or urine leaking.

Participants MUST have:
* Access to the internet/smart phone.
* Ability to relay valid information, actively participate in the study and provide
informed consent.

Participants must NOT have:
* Neurologic disease or injury, including (but not limited to) : Stroke, Alzheimer’s,
Parkinson’s, Multiple Sclerosis, traumatic brain injury, spinal cord injury, or
history of brain or complicated spinal surgery.
* History of pelvic cancer or undergoing any form of current cancer treatment.
* Diagnosis of pelvic pain, interstitial cystitis, chronic prostatitis, or chronic
orchalgia.
* Gross hematuria or visible blood in urine.
* Current urinary tract infection or current sexually-transmitted infection.
* Participants must not be using medication specifically to treat bladder
dysfunction.
* Difficulty reading or communicating in English.

Contact

Brenda Vicars
(206) 598-3293

Additional Study Details

Full Study Title
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Urinary Urgency Phenotyping Protocol

Study ID: STUDY00009656: LURN II
Start Date: 02/17/2021
End Date: 01/01/2024

Investigator(s)
Claire Yang, MD

Accepts Healthy Volunteers?
Yes

Study Site(s)

University of Washington Medical Center – Montlake

1959 NE Pacific St Surgery Pavilion – Urology Clinic
Seattle, Washington 98195



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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