30 Apr Testing AG019 and teplizumab in newly diagnosed type 1 diabetes patients
AG019 is a new drug that may interrupt the autoimmune attack on insulin-producing cells in the pancreas during type 1 diabetes. The drug teplizumab (Anti-CD3) has shown value in earlier studies in preserving insulin-producing cells.
The purpose of this study is to investigate if two different doses of AG019 are safe and tolerable when given alone or in combination with teplizumab, in patients recently diagnosed with type 1 diabetes.
You may be eligible to participate if:
– you are 12 year to 17 years old.
– you have been diagnosed with type 1 diabetes within 120 days.
– you test positive for at least one diabetes-related autoantibody.
– you are in good general health
Additional Study Details
Full Study Title
A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recently Diagnosed Type 1 Diabetes Mellitus (T1D)
Investigator: Carla Greenbaum, MD
Accepts Healthy Volunteers?
Benaroya Research Institute
1201 Ninth Ave
Seattle, Washington 98101