Quick Links

The QUEST Post-Amputation Pain Study

The QUEST Post-Amputation Pain Study

This clinical research study will evaluate whether electrical nerve block is a safe and effective treatment option for patients with post-amputation pain.

We are seeking volunteers who have lower limb pain related to an amputation. Participants chosen for our study will help us evaluate the effectiveness of an investigational medical device for the management of post-amputation pain. Medical care will be provided by professionals dedicated to finding relief for the kin of pain you suffer from.

Eligible participants will be implanted with an investigational device. The device includes a Cuff Electrode, which will be gently coiled around your nerve, and a Generator, which is similar to a pacemaker. Together they will deliver an electrical signal to the nerve.

Study participants will:
-Undergo surgery to implant the medical device
-Maintain a daily diary of pain
-Come to the clinic approximately once per month for a year
-Sign an informed consent form
-Provide medical records

You will not be charged for any study related appointments or procedures. Eligible participants will receive modest compensation for time and travel.

Your participation may benefit other people in the future; the medical device being tested may relieve amputation pain without solely on medication.

Participant Eligibility

You may qualify to take part in this clinical study if you have:

– One amputated lower limb
– Frequent and recurring pain which resulted from amputation
– 21 years of age or older


Jason Caucutt
(206) 616-3175

Additional Study Details

Full Study Title
High-Frequency Nerve Block for Post-Amputation Pain: A Pivotal Study

Study ID: 20141005
Start Date: 05/01/2018
End Date: 05/26/2021

Jiang Wu, MD
Andrew Ko, MD

Accepts Healthy Volunteers?

Study Site(s)

UW Center for Pain Relief

4225 Roosevelt Way NE 4th Floor
Seattle, Washington 98195

Harborview Hospital

325 9th Ave
Seattle, Washington 98104
United States

Map It


Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.