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WEB Study (Weight Effects on Brain Health Study)

WEB Study (Weight Effects on Brain Health Study)

WEB study is a longitudinal study that will examine changes that may occur in the brain following obesity treatment.
We are currently recruiting:

  1. People who are eligible to participate in the behavioral weight loss intervention (BMI greater than 30, determined by phone screen)
  2. People planning to have weight loss surgery with their health care team (study does not provide surgery)

Participants will have 5-6 in-person study visits at University of Washington in Seattle, Washington, South Lake Union research facilities over 18 months. Visits vary in length; some visits take about one hour and some take about 6-7 hours. Study visit procedures include fasting and non-fasting blood draws, MRIs, DXA scans, complete questionnaires, and other research activities. In addition, the behavioral weight loss group will participate in a six-month dietary intervention based at Fred Hutchinson.

Participants may earn up to $475 for completing research procedures over the course of the study.

Participant Eligibility

Eligibility will be determined by phone screening questions and confirmed following an in-person screening visit.

-Age 25-64
-Able to have an MRI
-Available to participate in a study with several appointments over 18 months
-Not currently using nicotine containing products daily
-No severe food allergies
-No history of weight loss surgery
-Not taking insulin or other medications known to alter metabolism
-No major medical conditions
-No history of or current eating disorder
-Not currently taking weight loss medications or currently enrolled in weight loss program



Additional Study Details

Full Study Title
A Cohort Study of Weight Loss and Gliosis

Study ID: 2978
Start Date: 02/01/2019
End Date: 06/04/2021

Ellen Schur, MD, MS
Mario Kratz, PhD, MS

Accepts Healthy Volunteers?

Study Site(s)

University of Washington

Republican St
Seattle, Washington 98109

Fred Hutchinson

Fairview Ave N
Seattle Washington 98109


Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.