{"id":4709,"date":"2021-04-20T16:26:56","date_gmt":"2021-04-20T23:26:56","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=4709"},"modified":"2021-04-22T11:30:11","modified_gmt":"2021-04-22T18:30:11","slug":"biohaven-302-ocd-research-study","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/biohaven-302-ocd-research-study\/","title":{"rendered":"Biohaven 302 OCD Research Study"},"content":{"rendered":"
<\/div>\n

To evaluate the efficacy of troriluzole as adjunctive therapy compared to placebo in subjects with OCD who have had an inadequate response to their current OCD treatment based on the change in their Y-BOCS score
\nTo assess the safety and tolerability of troriluzole, relative to placebo, in subjects with OCD
\nTo evaluate the efficacy of troriluzole compared to placebo on functional disability as measured by the Sheehan Disability Scale (SDS)
\nTo evaluate the efficacy of troriluzole compared to placebo on global clinical condition as measured by the Clinical Global Impression Severity Scale (CGI-S)<\/p>\n

This is a Phase 3 study.<\/p>\n

Total duration of study is 10 weeks and then a return in 2 weeks after discontinuing medication for follow up safety visit.
\nThis study has an open-label extension for those elgible.<\/p>\n

Participant Eligibility<\/h3>\n

Males and females between the ages of 18 and 65 inclusive
\nMust have primary diagnosis of OCD
\nDuration of OCD must be at least 1 year
\nSubjects must be currently experiencing non-response or inadequate response to their current OSC medication
\nSubjects should currently be on an SSRI (with exception of fluvoxamine) or clomipramine, venlafaxine, or desvenlafaxine for an adequate duration of at least 8 weeks
\nSubjects not on above medication can be prescreened at site<\/p>\n

Contact<\/h3>\n

Enroll
\n(425) 453-0404 x_____<\/p>\n

<\/p>\n

Additional Study Details<\/h3>\n

Full Study Title<\/strong>
\nA Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Troriluzole in Obsessive Compulsive Disorder
\n<\/span><\/p>\n

Study ID:<\/strong> SSU00136057<\/div>\n
ClinicalTrials.gov Link:<\/strong> NCT04641143<\/a><\/div>\n
<\/div>\n
Start Date:<\/strong> 12\/22\/2022<\/div>\n
End Date:<\/strong> 03\/17\/2023<\/div>\n
<\/div>\n

Investigator(s)<\/strong>
\nArifulla Khan
\n<\/span>
\nAccepts Healthy Volunteers?<\/strong>
\nNo<\/span><\/p>\n

Study Site(s)<\/strong> <\/p>\n

\n

Northwest Clinical Research Center<\/h4>\n

1951 152nd Place Northeast Suite 200
\nBellevue, Washington 98007<\/p><\/div>\n

\n

<\/h4>\n<\/p><\/div>\n
<\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

To evaluate the efficacy of troriluzole as adjunctive therapy compared to placebo in subjects with OCD who have had an inadequate response to their current OCD treatment based on the change in their Y-BOCS score To assess the safety and tolerability of troriluzole, relative to…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[1227,1226,673],"class_list":["post-4709","post","type-post","status-publish","format-standard","hentry","category-mental-health-and-behavior","tag-compulsive-personality-disorder","tag-obsessive-compulsive-disorder","tag-ocd"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/4709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=4709"}],"version-history":[{"count":1,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/4709\/revisions"}],"predecessor-version":[{"id":4710,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/4709\/revisions\/4710"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=4709"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=4709"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=4709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}