{"id":5121,"date":"2022-06-02T07:42:38","date_gmt":"2022-06-02T14:42:38","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=5121"},"modified":"2024-01-16T15:38:45","modified_gmt":"2024-01-16T23:38:45","slug":"abc-ct-cs","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/abc-ct-cs\/","title":{"rendered":"ABC-CT CS"},"content":{"rendered":"<div class=\"box summary\"><\/div>\n<p>This is a multicenter longitudinal study that aims to validate a set of measures that were previously identified as promising candidate biomarkers and\/or sensitive and reliable objective measures of social function in ASD for potential use in clinical trials. The confirmation study will repeat the data collection and analysis protocols from the original ABC-CT study.<\/p>\n<p>The goal of this consortium is to establish tools that can be used as biomarkers and\/or sensitive and reliable objective assays of social function in autism spectrum disorder (ASD) clinical trials. Specifically, we aim to accelerate the development of effective treatments for social function in ASD by validating (a) outcome measures that will be sensitive and reliable assessments of response to treatment<br \/>\nand (b) biomarkers in the domains of electroencephalography (EEG), eye-tracking (ET) and behavioral measures of social function to reduce heterogeneity of samples via stratification.<\/p>\n<p>Children will be assessed across three time points (T1: Baseline, T2: 6 weeks, T3: 24 weeks) using clinician and caregiver assessments along with a battery of conceptually related EEG and ET tasks and independent ratings of clinical status.<\/p>\n<h3>Participant Eligibility<\/h3>\n<p>Children between 6 and 11 years \u2013 who have been diagnosed with autism spectrum disorder<\/p>\n<p>Children between 6 and 11 years \u2013 who are typically developing and no siblings with ASD<\/p>\n<h3>Contact<\/h3>\n<p>Meghna Manoj and Grace Mattson<br \/>\n206-221-7688<\/p>\n<div class=\"box \"><\/p>\n<h3 class=\"dets\">Additional Study Details<\/h3>\n<p><span class=\"st\"><strong>Full Study Title<\/strong><br \/>\nAutism Biomarkers Consortium for Clinical Trials: Confirmation Study<br \/>\n<\/span><\/p>\n<div class=\"lhalf sid\"><strong>Study ID:<\/strong> 2000031989<\/div>\n<div class=\"rhalf ctlink\"><strong>ClinicalTrials.gov Link:<\/strong> <a class=\"link-outbound\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT05294705\" target=\"_blank\" rel=\"noopener\">NCT05294705<\/a><\/div>\n<div class=\"clear\"><\/div>\n<div class=\"lhalf start\"><strong>Start Date:<\/strong> 04\/06\/2022<\/div>\n<div class=\"rhalf end\"><strong>End Date:<\/strong> 04\/06\/2023<\/div>\n<div class=\"clear\"><\/div>\n<p><span class=\"pi\"><strong>Investigator(s)<\/strong><br \/>\nNatalia Kleinhans<br \/>\nJames McPartland<br \/>\n<\/span><br \/>\n<span class=\"healthy\"><strong>Accepts Healthy Volunteers?<\/strong><br \/>\nYes<\/span><\/p>\n<p><strong class=\"ssites\">Study Site(s)<\/strong><\/p>\n<div class=\"lhalf site1\">\n<h4>University of Washington<\/h4>\n<p>1701 NE Columbia Rd<br \/>\nSeattle, Washington 98195<\/p>\n<\/div>\n<div class=\"rhalf site2\">\n<h4><\/h4>\n<\/div>\n<div class=\"clear\"><\/div>\n<p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>This is a multicenter longitudinal study that aims to validate a set of measures that were previously identified as promising candidate biomarkers and\/or sensitive and reliable objective measures of social function in ASD for potential use in clinical trials. The confirmation study will repeat the&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,5,8,17],"tags":[],"class_list":["post-5121","post","type-post","status-publish","format-standard","hentry","category-healthy-volunteers","category-brain-and-nervous-system","category-child-health","category-mental-health-and-behavior"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5121","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=5121"}],"version-history":[{"count":5,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5121\/revisions"}],"predecessor-version":[{"id":5582,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5121\/revisions\/5582"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=5121"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=5121"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=5121"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}