{"id":5376,"date":"2023-03-31T08:59:34","date_gmt":"2023-03-31T15:59:34","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=5376"},"modified":"2025-10-07T08:24:24","modified_gmt":"2025-10-07T15:24:24","slug":"hiv-reservoir-in-blood-and-inflammation-in-the-intestine","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/hiv-reservoir-in-blood-and-inflammation-in-the-intestine\/","title":{"rendered":"HIV reservoir in blood and inflammation in the intestine."},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<div class=\"box summary\"><\/div>\n<p>The purpose of this study is to understand whether HIV medications can produce inflammation in the intestine (\u201cyour gut\u201d) and affect the size of the HIV reservoir in people living with HIV.<\/p>\n<p>There are two study visits:<br \/>\nGeneral health assessment and medical history<br \/>\nEndoscopy and biopsies from both the rectum and the duodenum (small intestine).<br \/>\nBlood samples (from vein).<\/p>\n<p>Participants will receive up to $400<\/p>\n<h3>Participant Eligibility<\/h3>\n<p>Age 18-65<br \/>\nHIV positive<br \/>\nOn a stable regimen of antiretroviral therapy for at least one year<\/p>\n<h3>Contact<\/h3>\n<p><span data-olk-copy-source=\"MessageBody\">Clay Youngblood<\/span><br \/>\n(206) 744-3732<\/p>\n<div class=\"box \">\n<h3 class=\"dets\">Additional Study Details<\/h3>\n<p><span class=\"st\"><strong>Full Study Title<\/strong><br \/>\nComparing immune activation and latent HIV reservoir size between people living with HIV (PWH) on tenofovir-containing versus NRTI-sparing ART<br \/>\n<\/span><\/p>\n<div class=\"lhalf sid\"><strong>Study ID:<\/strong> STUDY00011699<\/div>\n<div class=\"rhalf ctlink\"><strong>ClinicalTrials.gov Link:<\/strong> <a class=\"link-outbound\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT05584397\" target=\"_blank\" rel=\"noopener\">NCT05584397<\/a><\/div>\n<div class=\"clear\"><\/div>\n<div class=\"lhalf start\"><strong>Start Date:<\/strong> 12\/14\/2021<\/div>\n<div class=\"rhalf end\"><strong>End Date:<\/strong> 11\/14\/2023<\/div>\n<div class=\"clear\"><\/div>\n<p><span class=\"pi\"><strong>Investigator(s)<\/strong><br \/>\nGerman Gornalusse, PhD<br \/>\n<\/span><br \/>\n<span class=\"healthy\"><strong>Accepts Healthy Volunteers?<\/strong><br \/>\nNo<\/span><\/p>\n<p><strong class=\"ssites\">Study Site(s)<\/strong><\/p>\n<div class=\"lhalf site1\">\n<h4>Harborview Medical Center<\/h4>\n<p>325 9th Avenue<br \/>\nSeattle, Washington 98104<\/p>\n<\/div>\n<div class=\"rhalf site2\">\n<h4><\/h4>\n<\/div>\n<div class=\"clear\"><\/div>\n<p><\/div>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;&#8221;] The purpose of this study is to understand whether HIV medications can produce inflammation in the intestine (\u201cyour gut\u201d) and affect the size of the HIV reservoir in people living with HIV. There are two study&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14,3,10,20],"tags":[1270,1375,258,884],"class_list":["post-5376","post","type-post","status-publish","format-standard","hentry","category-allergies-immune-system","category-blood-lymphatic-system","category-digestive-system-and-liver","category-reproductive-and-sexual-health","tag-aids","tag-antiretroviral","tag-hiv","tag-immune-system"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=5376"}],"version-history":[{"count":4,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5376\/revisions"}],"predecessor-version":[{"id":5957,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5376\/revisions\/5957"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=5376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=5376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=5376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}