{"id":5766,"date":"2024-10-23T13:39:46","date_gmt":"2024-10-23T20:39:46","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=5766"},"modified":"2025-10-23T09:12:54","modified_gmt":"2025-10-23T16:12:54","slug":"drug-excretion-in-breast-milk","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/drug-excretion-in-breast-milk\/","title":{"rendered":"Drug Excretion in Breast Milk"},"content":{"rendered":"

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=””]<\/p>\n

<\/div>\n

This study explores how medications enter breast milk, which is not yet fully understood. We will investigate this process using the medication cimetidine, an over-the-counter heartburn medication that is safe for use while breastfeeding and has few side effects.<\/p>\n

Participants will give consent during pregnancy, but all study activities will occur after delivery.<\/p>\n

Participation in the study involves three separate study days, each lasting 12-13 hours. These days will be scheduled at 3-5 weeks, 3-4 months, and 6-8 months postpartum. On each study day, participants will take a single dose of cimetidine and provide samples of blood, urine, and breast milk. Participants are welcome to bring their infants to the study days.<\/p>\n

Participants who complete all study procedures will receive $700 in compensation.<\/p>\n

Participant Eligibility<\/h3>\n

Inclusion Criteria:
\nBetween the ages of 18-50 years old
\nGenerally healthy
\nPlanning to lactate for at least six months postpartum
\nAble to provide written informed consent<\/p>\n

Exclusion Criteria:
\nMultiple gestation (twins, triplets, etc.)
\nHypersensitivity to cimetidine
\nReceiving medication(s) known to interact with cimetidine
\nKnown kidney disease
\nKnown liver disease
\nInability to fast for 4 hours prior to the study
\nUse of tobacco or other nicotine containing products<\/p>\n

Contact<\/h3>\n

Lily Gutierrez
\n(206) 543-5600<\/span><\/p>\n

\n

Additional Study Details<\/h3>\n

Full Study Title<\/strong>
\nDrug Excretion in Breast Milk
\n<\/span><\/p>\n

Study ID:<\/strong> STUDY00018397<\/div>\n
ClinicalTrials.gov Link:<\/strong> NCT06056583<\/a><\/div>\n
<\/div>\n
Start Date:<\/strong> 07\/25\/2023<\/div>\n
End Date:<\/strong> 09\/30\/2028<\/div>\n
<\/div>\n

Investigator(s)<\/strong>
\nDr. Mary Hebert, PharmD, FCCP
\nDr. Joanne Wang, PhD
\nDr. Emily Fay, MD
\n<\/span>
\nAccepts Healthy Volunteers?<\/strong>
\nYes<\/span><\/p>\n

Study Site(s)<\/strong><\/p>\n

\n

University of Washington<\/h4>\n

1959 NE Pacific St
\nSeattle, Washington 98195<\/p>\n<\/div>\n

\n

<\/h4>\n<\/div>\n
<\/div>\n

<\/div>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=””] This study explores how medications enter breast milk, which is not yet fully understood. We will investigate this process using the medication cimetidine, an over-the-counter heartburn medication that is safe for use while breastfeeding and has…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,20,24],"tags":[949,1594,1595,1593,1558],"class_list":["post-5766","post","type-post","status-publish","format-standard","hentry","category-healthy-volunteers","category-reproductive-and-sexual-health","category-womens-health","tag-breastfeeding","tag-breastmilk","tag-drugs-in-breastmilk","tag-lactation","tag-postpartum"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=5766"}],"version-history":[{"count":5,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5766\/revisions"}],"predecessor-version":[{"id":5961,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5766\/revisions\/5961"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=5766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=5766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=5766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}