{"id":5801,"date":"2025-01-15T07:11:27","date_gmt":"2025-01-15T15:11:27","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=5801"},"modified":"2026-03-09T15:06:10","modified_gmt":"2026-03-09T22:06:10","slug":"cogit-2-trial","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/cogit-2-trial\/","title":{"rendered":"COGIT-2 Trial"},"content":{"rendered":"

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<\/div>\n

This study is being conducted to evaluate if cognitive training can improve cognitive performance in participants with memory loss. This study will evaluate the effects of crossword puzzles training and health education for improvement in everyday cognitive performance over an 18-month period.<\/p>\n

If you join the study, you will be assigned to 1 of 3 treatment conditions: crossword puzzles 4 times per week, crossword puzzles once per week, or health education. During the study you will need to come to in-person study visits approximately every 3 months for cognitive testing, questionnaires, blood draws, and MRI scans. Participants will be compensated for their time.<\/p>\n

Participant Eligibility<\/h3>\n

To be eligible, you need to be:
\n– Between the ages of 55-89
\n– Have been diagnosed with Mild Cognitive Impairment, OR you have concerns about your memory
\n– English speaking
\n– Not taking any anti-amyloid medications for Alzheimer\u2019s disease, such as Lequembi (lecanemab) or Kisunla (donanemab)
\n– Have a relative, friend, or other caregiver who can provide information about your functioning, either in-person or by phone.
\n– Not currently doing crosswords, Sudoku, or other cognitive training methods like Brain HQ or Lumosity on a regular basis more than once per week<\/p>\n

Contact<\/h3>\n

Hanson Lab
\n(206) 897-1701<\/p>\n

<\/p>\n

Additional Study Details<\/h3>\n

Full Study Title<\/strong>
\nCognitive Training and Neuroplasticity in Mild Cognitive Impairment
\n<\/span><\/p>\n

Study ID:<\/strong> 20240282<\/div>\n
ClinicalTrials.gov Link:<\/strong> NCT06601933<\/a><\/div>\n
<\/div>\n
Start Date:<\/strong> 07\/17\/2025<\/div>\n
End Date:<\/strong> 02\/28\/2029<\/div>\n
<\/div>\n

Investigator(s)<\/strong>
\nDr. Angela Hanson
\n<\/span>
\nAccepts Healthy Volunteers?<\/strong>
\nNo<\/span><\/p>\n

Study Site(s)<\/strong><\/p>\n

\n

Harborview Medical Center – Alzheimer’s Disease Research Center (ADRC)<\/h4>\n

325 9th Ave
\nSeattle, Washington 98104
\nUnited States<\/p>\n<\/div>\n

\n

University of Washington South Lake Union Diabetes Institute Clinical Research Unit (SLU DICRU)<\/h4>\n

750 Republican Street
\nSeattle, Washington 98109
\nUnited States<\/p>\n<\/div>\n

<\/div>\n

<\/div>\n

[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=””] This study is being conducted to evaluate if cognitive training can improve cognitive performance in participants with memory loss. This study will evaluate the effects of crossword puzzles training and health education for improvement in everyday…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[487,1210],"class_list":["post-5801","post","type-post","status-publish","format-standard","hentry","category-brain-and-nervous-system","tag-alzheimers-disease","tag-mild-cognitive-impairment"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5801","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=5801"}],"version-history":[{"count":4,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5801\/revisions"}],"predecessor-version":[{"id":6012,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/5801\/revisions\/6012"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=5801"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=5801"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=5801"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}