{"id":5992,"date":"2025-12-23T08:13:10","date_gmt":"2025-12-23T16:13:10","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=5992"},"modified":"2025-12-23T08:49:11","modified_gmt":"2025-12-23T16:49:11","slug":"nasal-spray-covid-19-vaccine-study","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/nasal-spray-covid-19-vaccine-study\/","title":{"rendered":"Nasal Spray COVID-19 Vaccine Study"},"content":{"rendered":"

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Study Description:
\nKaiser Research is inviting volunteers to join a research study of an investigational nasal spray vaccine against COVID-19 to help evaluate the vaccine\u2019s safety, tolerability, and immune response. Enrollment may be ongoing for several months. Volunteers do not need to be Kaiser members.<\/p>\n

What does participation involve?
\n\u2022 One dose (by nose spray into both nostrils) of the investigational study vaccine
\n\u2022 8 study visits at our research clinic in downtown Seattle and 1 phone visit over a 6- to 7-month period
\n\u2022 Nasal swab(s) at every research clinic visit; blood draw and saliva collection at most visits
\n\u2022 $100 compensation for each of the first two research clinic visits (screening and enrollment) and $50 for each follow-up visit
\n\u2022 Answer questions on a worksheet about possible vaccine reactions every evening for at least 8 days after the study vaccine
\n\u2022 Free parking in our research clinic building\u2019s garage or bus tickets provided at each visit<\/p>\n

Participant Eligibility<\/h3>\n

Participant Eligibility:
\n\u2022 Healthy adults age 18-64
\n\u2022 Previous COVID-19 infection or vaccine must have been 16+ weeks before enrollment
\n\u2022 Non-smokers (including vaping)
\n\u2022 No intranasal steroids within 30 days of enrollment and throughout the study
\n\u2022 Agree to have samples stored for secondary research
\n\u2022 No intranasal drug use
\n\u2022 Hepatitis B, Hepatitis C, and HIV negative
\n\u2022 No significant lung conditions
\n\u2022 No medical conditions or medications that affect the immune system
\n\u2022 There are other conditions that may make you ineligible for this study<\/p>\n

Contact<\/h3>\n

KPWHRI https:\/\/redcap.link\/ib29whs7<\/a>
\n(206) 287-2061<\/p>\n

\n

Additional Study Details<\/h3>\n

Full Study Title<\/strong>
\nA Phase 1, Open-Label, Safety and Immunogenicity Trial of Boost-2867, an IgG-Fc-RBD Fusion Protein Next Generation SARS-CoV-2 Booster Vaccine, Via Intranasal and Intramuscular Routes in Previously Vaccinated Adults
\n<\/span><\/p>\n

Study ID:<\/strong> Advarra Pro00090304<\/div>\n
ClinicalTrials.gov Link:<\/strong> NCT07221162<\/a><\/div>\n
<\/div>\n
Start Date:<\/strong> 11\/26\/2025<\/div>\n
End Date:<\/strong> 05\/31\/2025<\/div>\n
<\/div>\n

Investigator(s)<\/strong>
\nLisa A. Jackson, MD, MPH
\n<\/span>
\nAccepts Healthy Volunteers?<\/strong>
\nYes<\/span><\/p>\n

Study Site(s)<\/strong><\/p>\n

\n

Kaiser Permanente Washington Health Research Institute<\/h4>\n

Seattle, Washington 98101<\/p>\n<\/div>\n

\n

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