{"id":6019,"date":"2026-03-26T07:29:16","date_gmt":"2026-03-26T14:29:16","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=6019"},"modified":"2026-03-26T07:29:16","modified_gmt":"2026-03-26T14:29:16","slug":"br-prospect-radiolabeled-platelet-study","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/br-prospect-radiolabeled-platelet-study\/","title":{"rendered":"BR-PROSPECT Radiolabeled Platelet Study"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<div class=\"box summary\"><\/div>\n<p>This is a platelet transfusion study. The primary purpose of this study is to determine if Biotin (vitamin B7) is an effective way to label platelets in survival and recovery studies. This study involves using a radioactive material as well as Biotin added to your platelets to track platelets in your blood. Your platelets will be collected using an apheresis procedure, labeled with biotin, and stored for 3 days. After the storage period, a radioactive material will be added to a small amount of your stored biotin-treated platelets. Your radiolabeled platelets will be given back to you and follow-up blood draws will be done to see how many of your platelets are circulating.<\/p>\n<p>There will be a total of 12 visits over 180 days days. Each study visit lasts from 30 minutes to 3 hours.<br \/>\nStudy visits will occur at Bloodworks Northwest &#8211; 1551 Eastlake Ave. East, Suite 100, Seattle, WA 98102.<br \/>\nParticipants will be compensated up to $1500.00 for time involved in the study.<\/p>\n<h3>Participant Eligibility<\/h3>\n<p>Inclusion Criteria:<br \/>\n\u2022 At least 18 years of age.<br \/>\n\u2022 Be in good health.<br \/>\n\u2022 Weigh at least 114 lbs.<br \/>\n\u2022 Meet study criteria for an apheresis platelet collection.<br \/>\n\u2022 Not be taking medication known to interfere with platelet function such as aspirin, nonsteroidal anti-inflammatory drugs such as ibuprofen (Advil, Motrin) or naproxen (Aleve), or platelet inhibitors given for heart disease.<br \/>\n\u2022 Test negative for infectious diseases as part of blood donor screening.<br \/>\nExclusion Criteria:<br \/>\n\u2022 Acute or chronic health conditions that may affect study results.<br \/>\n\u2022 Pregnant or nursing females.<br \/>\n\u2022 Test positive for cocaine or amphetamine use by urine drug screen test.<br \/>\n\u2022 Not have a spleen.<br \/>\n\u2022 History of known hypersensitivity to indium or chromium.<br \/>\n\u2022 On other investigation drug studies within the past 28 days.<\/p>\n<h3>Contact<\/h3>\n<p>Patricia Klotz<br \/>\n(206) 568-2238<\/p>\n<div class=\"box \">\n<h3 class=\"dets\">Additional Study Details<\/h3>\n<p><span class=\"st\"><strong>Full Study Title<\/strong><br \/>\nBR-PROSPECT: Biotin and Radiolabeling for the Platelet Recovery, Survival, and Post-transfusion Evaluation of Changes<br \/>\n<\/span><\/p>\n<div class=\"lhalf sid\"><strong>Study ID:<\/strong> 1405996<\/div>\n<div class=\"rhalf ctlink\"><strong>ClinicalTrials.gov Link:<\/strong> <a class=\"link-outbound\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/record\/Pending\" target=\"_blank\" rel=\"noopener\">Pending<\/a><\/div>\n<div class=\"clear\"><\/div>\n<div class=\"lhalf start\"><strong>Start Date:<\/strong> 03\/11\/2026<\/div>\n<div class=\"rhalf end\"><strong>End Date:<\/strong> 07\/31\/2026<\/div>\n<div class=\"clear\"><\/div>\n<p><span class=\"pi\"><strong>Investigator(s)<\/strong><br \/>\nMoritz Stolla, MD<br \/>\n<\/span><br \/>\n<span class=\"healthy\"><strong>Accepts Healthy Volunteers?<\/strong><br \/>\nYes<\/span><\/p>\n<p><strong class=\"ssites\">Study Site(s)<\/strong><\/p>\n<div class=\"lhalf site1\">\n<h4>Bloodworks Research Institute<\/h4>\n<p>1551 Eastlake Ave E Suite 100<br \/>\nSeattle, Washington 98102<\/p>\n<\/div>\n<div class=\"rhalf site2\">\n<h4><\/h4>\n<\/div>\n<div class=\"clear\"><\/div>\n<p><\/div>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;&#8221;] This is a platelet transfusion study. The primary purpose of this study is to determine if Biotin (vitamin B7) is an effective way to label platelets in survival and recovery studies. This study involves using a&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[1705,1706,1707],"class_list":["post-6019","post","type-post","status-publish","format-standard","hentry","category-healthy-volunteers","tag-apheresis-platelet","tag-biotin","tag-radiolabeled-platelets"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=6019"}],"version-history":[{"count":3,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6019\/revisions"}],"predecessor-version":[{"id":6022,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6019\/revisions\/6022"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=6019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=6019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=6019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}