{"id":6025,"date":"2026-04-13T08:32:37","date_gmt":"2026-04-13T15:32:37","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=6025"},"modified":"2026-04-13T08:32:37","modified_gmt":"2026-04-13T15:32:37","slug":"reset-t1d","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/reset-t1d\/","title":{"rendered":"Reset T1D"},"content":{"rendered":"<div class=\"box summary\"><\/div>\n<p>TrialNet is studying rezpegaldesleukin to see if it can help the body continue making insulin in people newly diagnosed with type 1 diabetes (TID) by stimulating regulatory T cells to restore immune balance.<\/p>\n<p>Rezpegaldesleukin is already being studied in people with other autoimmune diseases like psoriasis and eczema. This is the first time it is being studied in people with TID.<\/p>\n<p>Like all clinical research, there are benefits and risks to participating in this study. Before you join the study, a TrialNet team member will explain all potential benefits and risks and answer your questions.<\/p>\n<h3>Participant Eligibility<\/h3>\n<p>-Newly diagnosed with T1D (in the past 3 months)<br \/>\n-Ages 18 to 45<\/p>\n<p>Your screening tests show:<br \/>\n-1 or more diabetes-related autoantibody<br \/>\n-Detectable C-peptide during a mixed meal tolerance test (MMTT)<\/p>\n<p>A research team member will go over the full list of eligibility criteria with you before your screening visit.<\/p>\n<h3>Contact<\/h3>\n<p>the Outreach Team<br \/>\n(800) 888-4187<\/p>\n<div class=\"box \"><\/p>\n<h3 class=\"dets\">Additional Study Details<\/h3>\n<p><span class=\"st\"><strong>Full Study Title<\/strong><br \/>\nRezpegaldesleukin for Newly Diagnosed T1D Study (RESET T1D)<br \/>\n<\/span><\/p>\n<div class=\"lhalf sid\"><strong>Study ID:<\/strong> TN36<\/div>\n<div class=\"rhalf ctlink\"><strong>ClinicalTrials.gov Link:<\/strong> <a class=\"link-outbound\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT07142252\" target=\"_blank\" rel=\"noopener\">NCT07142252<\/a><\/div>\n<div class=\"clear\"><\/div>\n<div class=\"lhalf start\"><strong>Start Date:<\/strong> 03\/25\/2026<\/div>\n<div class=\"rhalf end\"><strong>End Date:<\/strong> 05\/25\/2028<\/div>\n<div class=\"clear\"><\/div>\n<p><span class=\"pi\"><strong>Investigator(s)<\/strong><br \/>\nKurt Griffin, MD<br \/>\n<\/span><br \/>\n<span class=\"healthy\"><strong>Accepts Healthy Volunteers?<\/strong><br \/>\nNo<\/span><\/p>\n<p><strong class=\"ssites\">Study Site(s)<\/strong><\/p>\n<div class=\"lhalf site1\">\n<h4>Benaroya Research Institute<\/h4>\n<p>1201 9th Ave<br \/>\nSeattle, Washington 98101<\/p>\n<\/div>\n<div class=\"rhalf site2\">\n<h4><\/h4>\n<\/div>\n<div class=\"clear\"><\/div>\n<p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>TrialNet is studying rezpegaldesleukin to see if it can help the body continue making insulin in people newly diagnosed with type 1 diabetes (TID) by stimulating regulatory T cells to restore immune balance. Rezpegaldesleukin is already being studied in people with other autoimmune diseases like&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[323],"class_list":["post-6025","post","type-post","status-publish","format-standard","hentry","category-diabetes","tag-type-1-diabetes"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=6025"}],"version-history":[{"count":2,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6025\/revisions"}],"predecessor-version":[{"id":6027,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6025\/revisions\/6027"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=6025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=6025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=6025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}