{"id":6031,"date":"2026-04-22T09:24:06","date_gmt":"2026-04-22T16:24:06","guid":{"rendered":"https:\/\/www.iths.org\/participate\/?p=6031"},"modified":"2026-04-22T09:24:06","modified_gmt":"2026-04-22T16:24:06","slug":"a-study-of-brenipatide-in-participants-with-moderate-to-severe-alcohol-use-disorder-renew-alc-1","status":"publish","type":"post","link":"https:\/\/www.iths.org\/participate\/a-study-of-brenipatide-in-participants-with-moderate-to-severe-alcohol-use-disorder-renew-alc-1\/","title":{"rendered":"A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder (RENEW-ALC-1)"},"content":{"rendered":"<div class=\"box summary\"><\/div>\n<blockquote class=\"wp-embedded-content\" data-secret=\"nn32USmQ9q\"><p><a href=\"https:\/\/adai.uw.edu\/renew-alc\/\">Are you seeking to change your relationship with alcohol?<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" title=\"&#8220;Are you seeking to change your relationship with alcohol?&#8221; &#8212; Addictions, Drug &amp; Alcohol Institute\" src=\"https:\/\/adai.uw.edu\/renew-alc\/embed\/#?secret=JtgeEePduH#?secret=nn32USmQ9q\" data-secret=\"nn32USmQ9q\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will last approximately 56 weeks.<\/p>\n<h3>Participant Eligibility<\/h3>\n<p>&#8211; Aged 18 to 75 years.<br \/>\n&#8211; Looking for treatment and are motivated to stop or cut down on drinking.<br \/>\n&#8211; Someone who drank alcohol regularly for the past 30 days at levels specified by the study (call the study phone number to see if you may be eligible)<\/p>\n<h3>Contact<\/h3>\n<p>Kai Orozco<br \/>\n(206) 743-5286<\/p>\n<div class=\"box \"><\/p>\n<h3 class=\"dets\">Additional Study Details<\/h3>\n<p><span class=\"st\"><strong>Full Study Title<\/strong><br \/>\nA Phase 3, Multicenter, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Brenipatide Compared with Placebo for the Treatment of Adult Participants with Moderate-to-Severe Alcohol Use Disorder (RENEW-ALC-1)<br \/>\n<\/span><\/p>\n<div class=\"lhalf sid\"><strong>Study ID:<\/strong> Pro00089195<\/div>\n<div class=\"rhalf ctlink\"><strong>ClinicalTrials.gov Link:<\/strong> <a class=\"link-outbound\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT07219966\" target=\"_blank\" rel=\"noopener\">NCT07219966<\/a><\/div>\n<div class=\"clear\"><\/div>\n<div class=\"lhalf start\"><strong>Start Date:<\/strong> 01\/16\/2026<\/div>\n<div class=\"rhalf end\"><strong>End Date:<\/strong> 07\/31\/2026<\/div>\n<div class=\"clear\"><\/div>\n<p><span class=\"pi\"><strong>Investigator(s)<\/strong><br \/>\nMark Duncan, MD<br \/>\nMary Hatch, PhD<br \/>\n<\/span><br \/>\n<span class=\"healthy\"><strong>Accepts Healthy Volunteers?<\/strong><br \/>\nNo<\/span><\/p>\n<p><strong class=\"ssites\">Study Site(s)<\/strong><\/p>\n<div class=\"lhalf site1\">\n<h4>University of Washington Medical Center &#8211; Montlake<\/h4>\n<p>1959 NE Pacific St.<br \/>\nSeattle, Washington 98195<\/p>\n<\/div>\n<div class=\"rhalf site2\">\n<h4><\/h4>\n<\/div>\n<div class=\"clear\"><\/div>\n<p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Are you seeking to change your relationship with alcohol? The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will last approximately 56 weeks&#8230;.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,23],"tags":[232],"class_list":["post-6031","post","type-post","status-publish","format-standard","hentry","category-mental-health-and-behavior","category-wellness-lifestyle-and-environmental-health","tag-alcohol"],"_links":{"self":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6031","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/comments?post=6031"}],"version-history":[{"count":2,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6031\/revisions"}],"predecessor-version":[{"id":6033,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/posts\/6031\/revisions\/6033"}],"wp:attachment":[{"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/media?parent=6031"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/categories?post=6031"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iths.org\/participate\/wp-json\/wp\/v2\/tags?post=6031"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}