The Institute for Bioinformatics and Evolutionary Studies (IBEST) is an interdisciplinary research group at the University of Idaho focused on understanding the patterns and processes of evolution that occur over comparatively short periods of time. The hallmarks of IBEST research are the coupling of empirical and theoretical research, and a strong orientation toward rigorous testing of hypotheses. We place a high value on interdisciplinary collaborations that blend the expertise of biologists, biochemists, ecologists, evolutionary biologists, mathematicians, statisticians, bioinformaticians and computer scientists to examine the underpinnings of evolutionary biology. Many areas of current biological research rely on some form of high through genomic technologies, state of the art optical imaging, analysis, and bioinformatics. The IBEST Core Facilities are comprised of the Computational Resources Core, Genomics Resources Core and Optical Imaging Core. The Computational Resources Core contains the most sophisticated and powerful computing resources in the region, and is well-suited to complex computational tasks such as protein modeling, structure/function analysis, and ligand binding studies. In the Genomics Resources Core, researchers will find well-trained staff willing to consult on complex research projects. The Core is well equipped with instrumentation capable of handling DNA sequencing tasks, microarray based experiments, genotyping projects and many other project types. These state-of-the-art facilities are critical enabling resources for research being conducted in IBEST, the University of Idaho, and other institutions. The Optical Imaging Core consolidates optical microscopy and flow cytometry equipment for a solid base of state-of-the-art microscopy, imaging and image analysis equipment. The Core provides expertise to both on and off-campus researchers.