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Tetramer Core Laboratory, Benaroya Research Institute

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Tetramer Core Laboratory, Benaroya Research Institute, 1201 9th Ave, Seattle, WA 98101
1201 9th Avenue Seattle Washington 98101 US
(206) 625-7373 x68176(206) 625-7373 x68176

The Tetramer Core Laboratory provides MHC class II tetramer reagents for collaborators both within and outside BRI. These tetramers are synthetic protein conjugates that allow the direct detection of antigen specific T cells by flow cytometry. Tetramers produced in our facility have been used to detect CD4+ (helper) T cells and have facilitated the study of viral immunity, autoimmune diseases, allergic responses, and cancer. The class II MHC proteins are produced using stable insect cell cultures and purified by affinity chromatography. The purified proteins are loaded with exogenous peptide and conjugated using PE labeled streptavidin. In some cases we are able to provide T cell clones for use as experimental positive controls.

Center Contact
Eddie James
Available to
Anyone
Resource Type
Core Laboratory
Institution
Benaroya Research Institute at Virginia Mason
Institution
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South Lake Union Confocal Facility, 815 Mercer St, Seattle, WA 98109 1.11 mi
ronse@uw.eduronse@uw.edu
A Zeiss Confocal Microscope; model LSM510Meta is available to South Lake Union labs. The instrume...
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815 Mercer Street, Seattle, WA 98109, United States 1.11 mi
(206) 543-3061(206) 543-3061
The Bio-Molecular Imaging Center’s (BMIC) mission is to develop novel imaging techniques for anat...
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UW Medicine Proteomics Lab, South Lake Union, 815 Mercer St, Seattle, WA 98109 1.11 mi
(206) 616-0659(206) 616-0659
Our current focus is to provide mass spectrometry resources and computational support for the gre...
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Veterinary Diagnostic Laboratory, 815 Mercer St. Room 310N, Seattle, WA 98195 1.11 mi
(206) 685-3040(206) 685-3040
The University of Washington Veterinary Diagnostic Laboratory is staffed with veterinary patholog...
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Diabetes and Obesity Center of Excellence, UW Medicine Research, Republican St., Seattle, WA 98109 1.12 mi
(206) 221-0551(206) 221-0551
The Diabetes and Obesity Center of Excellence (DOCE), located at the South Lake Union research ca...
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Thomas Building, 1100 Fairview Ave N, Seattle, WA 98109 1.2 mi
(206) 667-4289(206) 667-4289
Electron Microscopy provides transmission electron microscopy and scanning electron microscopy fo...
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Fred Hutchinson Cancer Research Center, Thomas Building DE-740 1.2 mi
(206) 667-2714(206) 667-2714
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1100 Fairview Ave N ME-B143, Arnold Building Seattle, WA 98109 United States 1.2 mi
(206) 667-4639(206) 667-4639
The Fred Hutch Prevention Center is a state-of-the-art exercise facility, nutrition laboratory an...
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1100 Eastlake Building, E1-140 Seattle, WA 98109 1.31 mi
(206) 667-6612(206) 667-6612
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P.O. Box 19024, DE-550 Seattle, WA 98109 1.46 mi
(206) 667-6455(206) 667-6455
The Immune Monitoring Lab provides investigators with services and expertise for studies of cellu...
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P.O. Box 19024, B1-010 Seattle, WA 98109 1.46 mi
(206) 667-4314(206) 667-4314
The Arnold Library provides high quality, responsive services and resources in support of Fred Hu...
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P.O. Box 19024, DE-690 Seattle, WA 98109 1.46 mi
(206) 667-6195(206) 667-6195
Flow Cytometry offers a wide range of instrumentation, from single-laser benchtop analyzers to co...
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P.O. Box 19024, E1-415 Seattle, WA 98109 1.46 mi
(206) 667-4645(206) 667-4645
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PO Box 19024, DE-360 Seattle, Washington 98109 1.46 mi
(206) 667-6166(206) 667-6166
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P.O. Box 19024, DE-512 Seattle, WA 98109 1.46 mi
(206) 667-4205(206) 667-4205
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P.O. Box 19024, DE-740 Seattle, WA 98109 1.46 mi
(206) 667-2714(206) 667-2714
The Genomics Shared Resource provides expertise to support the generation of genomics-based data....
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P.O. Box 19024, J3-317 Seattle, WA 98109 1.46 mi
(206) 667-5879(206) 667-5879
This resource provides space for freezers used to store research samples, offers assistance with ...
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P.O. Box 19024, DE-352 Seattle, WA 98109 1.46 mi
(206) 667-1051(206) 667-1051
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(206) 221-1234(206) 221-1234
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3T Whole-Body MRI available at UW South Lake Union Bio-Medical Imaging Center.
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Cite ITHSThe Institute is supported by grants UL1 TR002319, KL2 TR002317, and TL1 TR002318 from the NIH National Center for Advancing Translational Sciences through the Clinical and Translational Science Awards Program (CTSA).

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