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Tetramer Core Laboratory, Benaroya Research Institute

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Tetramer Core Laboratory, Benaroya Research Institute, 1201 9th Ave, Seattle, WA 98101
1201 9th Avenue Seattle Washington 98101 US
(206) 625-7373 x68176(206) 625-7373 x68176

The Tetramer Core Laboratory provides MHC class II tetramer reagents for collaborators both within and outside BRI. These tetramers are synthetic protein conjugates that allow the direct detection of antigen specific T cells by flow cytometry. Tetramers produced in our facility have been used to detect CD4+ (helper) T cells and have facilitated the study of viral immunity, autoimmune diseases, allergic responses, and cancer. The class II MHC proteins are produced using stable insect cell cultures and purified by affinity chromatography. The purified proteins are loaded with exogenous peptide and conjugated using PE labeled streptavidin. In some cases we are able to provide T cell clones for use as experimental positive controls.

Center Contact
Eddie James
Available to
Anyone
Resource Type
Core Laboratory
Institution
Benaroya Research Institute at Virginia Mason
Institution
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Flow Cytometry Core Facility, Benaroya Research Institute, 1201 Ninth Avenue, Seattle, WA 98101 0 mi
(206) 342-6953(206) 342-6953
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Genome Resource Center, Benaroya Research Institute, 1201 9th Ave, Seattle, WA 98101 0 mi
(206) 287-1011(206) 287-1011
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Histology Imaging Core, Benaroya Research Institute, 1201 9th Ave, Seattle, WA 98101 0 mi
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Bioinformatics Core, Benaroya Research Institute, 1201 9th Ave, Seattle, WA 98101 0 mi
(206) 287-1009(206) 287-1009
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Benaroya Research Institute, 1201 Ninth Ave, Seattle, WA 98101 0 mi
(206) 342-6915(206) 342-6915
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Benaroya Research Institute, 1201 Ninth Ave, Seattle, WA 98101 0 mi
(206) 342-6500(206) 342-6500
Bloodworks
Bloodworks Northwest, 921 Terry Avenue, Seattle, WA 98104 0.17 mi
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University of Washington, College of Engineering, Seattle, WA 0.29 mi
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Kaiser Permanente Washington Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101 0.48 mi
(206) 287-2900(206) 287-2900
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CRAB, 1730 Minor Ave, STE 1900, Seattle, WA 98101 0.48 mi
(206) 652-9711(206) 652-9711
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Research Clinic, Kaiser Permanente Washington Health Research Institute, 1730 Minor Ave, Seattle, WA 98101 0.48 mi
(206) 287-4270(206) 287-4270
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University of Washington Center for AIDS and STDs, 325 Ninth Avenue, Seattle, WA 98104 0.49 mi
(206) 744-2238 or (206) 744-3785(206) 744-2238 or (206) 744-3785
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Lipid Clinic Northwest, Harborview, 325 9th Ave, Seattle, WA 98104 0.49 mi
(206) 520-5000(206) 520-5000
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Sexually Transmitted Infections Cooperative Research Center Laboratory core, Center for AIDS and STD, 325 9th Ave, Seattle, WA 98104 0.49 mi
(206) 744-4239(206) 744-4239
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Sociobehavioral and Prevention Research Core, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104 0.49 mi
(206) 543-6247(206) 543-6247
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Flow Cytometry Core Facility, Seattle Children's, 1900 9th Ave, Seattle, WA 98101 0.49 mi
(206) 884-7382(206) 884-7382
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Viral Core, Seattle Children's, 1900 9th Ave, Seattle, WA 98101 0.49 mi
(206) 884-8159(206) 884-8159
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Cite ITHSThe Institute is supported by grants UL1 TR002319, KL2 TR002317, and TL1 TR002318 from the NIH National Center for Advancing Translational Sciences through the Clinical and Translational Science Awards Program (CTSA).

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