Fostering and supporting both basic and clinical research in diabetes and related metabolic disorders...<\/p><\/div><\/div><\/div>\n\t\t\t\t\t\t
More Information<\/h3>Learn more about the Diabetes Research Center.<\/p><\/div><\/div>
Visit the Diabetes Research Center Site<\/a><\/div><\/div><\/div><\/div> <\/div> <\/div>[vc_empty_space height=”22px”][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_accordion active_tab=”” collapsible=”yes” style=”boxed_toggle”][vc_accordion_tab title=”Guidelines”][vc_column_text]<\/p>\nGuidelines<\/h5>\n\n- Successful applications will address a critical knowledge gap in type 1 or type 2 diabetes and represents a key step toward improvement in the treatment or prevention of disease. The project must demonstrate significant scientific merit and provide a vision of how it could evolve to a more substantial body of work.Examples of projects that would be considered responsive to this RFA include (but are not limited to):\n
\n- Investigations into basic cellular processes involved in glucose metabolism or the regulation of insulin signaling with the use of in vitro<\/em> cell culture models or primary cells.<\/li>\n
- Animal studies with dietary, pharmacologic or genetic interventions to improve our understanding of glucose tolerance, insulin sensitivity, pancreatic b-cell function or diabetic complications.<\/li>\n
- Human observational or epidemiological studies to identify risk factors for type 1 or type 2 diabetes or complications of diabetes.<\/li>\n
- Randomized controlled trials of diet or other lifestyle interventions, investigational drugs or devices, or other interventions (e.g. bariatric surgery) to assess their impact on glycemic control, glucose tolerance or complications of diabetes.<\/li>\n<\/ul>\n<\/li>\n
- Plan to spend your money in 1 year. No-cost extensions will not be allowed. ITHS faculty or staff may be listed as active research contributors on a case-by-case basis. Please consult with ITHS prior to application submission if your proposal includes ITHS faculty or staff.<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Eligible Investigators”][vc_column_text]<\/p>\n
Eligible Investigators<\/h5>\n
Faculty members at ITHS Partner Institutions, including the University of Washington, Fred Hutch Cancer Research Center, Seattle Children\u2019s Research Institute, and other academic institutions affiliated with the ITHS in the WWAMI (Washington, Wyoming, Alaska, Montana, Idaho) region are eligible to apply for this pilot award. Collaborations may extend outside the WWAMI region; however, funds may not be transferred outside the United States. ITHS-funded faculty and staff are ineligible to apply. An acting faculty member or instructor is eligible to apply only if the Department head provides a letter supporting the applicant\u2019s eligibility to serve as PI.<\/p>\n
All Investigators on the research team must be ITHS Members in order to apply. To become a member, please complete the ITHS Membership Form<\/a>.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Application Process”][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_column_text]<\/p>\nApplication Process<\/h5>\n
[\/vc_column_text][vc_column_text el_class=”hide”]<\/p>\n
\n\n\nA. Letter of Intent<\/h6>\n
The letter of intent form must be submitted through the ITHS website before submission of the application. The form includes information on\u00a0the applicant and any Co-Investigators or Community Partners, project title, and abstract (250 word maximum). Investigators who are invited to submit a full application will receive notice within two weeks.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=”” el_class=”hide”][vc_column_inner][vc_empty_space height=”12px”]Submit a Letter of Intent<\/i><\/a>[\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_empty_space height=”12px”][vc_column_text]<\/p>\nA. Application<\/h6>\n
The application must be submitted through the ITHS website.<\/p>\n
Applications will follow National Institutes of Health (NIH) formatting guidelines (see FAQ) and include:<\/p>\n95 KB<\/span>1) Cover Page<\/a>\n2)<\/strong> Project Title and Abstract (250 word maximum)
\n3)<\/strong> Research Plan, 2-pages (references do not count toward page limit)<\/div>\n57 KB<\/span>4)\u00a0Project Timeline – 1-page<\/a>\n5)<\/strong>\u00a0Budget and Budget Justification<\/strong>\u00a029 KB<\/span>5a) Budget<\/a> 37 KB<\/span>5b) Budget Justification<\/a><\/div>\n6)<\/strong> Letter(s) of Support<\/strong> –\u00a0<\/strong>Letters of Support are not required unless you are an instructor or acting faculty member.\u00a0<\/strong>If you are an instructor or acting faculty member, you will need to\u00a0include a letter supporting your eligibility to serve as PI from your Department head (or equivalent).<\/div>\n35 KB<\/span>7) NIH format Biosketches for all investigators (senior\/key personnel)<\/a>[\/vc_column_text][vc_column_text][vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′]<\/p>\nNot included in the above document:<\/h6>\n
Suggested Reviewers<\/strong> –\u00a0You will also be asked to provide five suggested reviewers, including the following information for each: 1) Name, 2) Title, 3) Institution\/Organization, and \u00a04) Email Address.<\/p>\nA general note about conflict of interest:<\/em> A reviewer would have a conflict of interest if they are the applicant’s mentor, dept. chair, spouse, or close relative; or if they currently work together on manuscripts, grants, or business ventures. Simply being in the same department or division is not, in and of itself, a conflict of interest.
\n[vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′][\/vc_column_text][vc_empty_space height=”22px”]Apply Now<\/i><\/a>[vc_empty_space height=”22px”][vc_column_text]<\/p>\nB. Timeline<\/h6>\n
[\/vc_column_text]
<\/p>\n\n- Letter of Intent Deadline<\/strong> – Date<\/li>\n
- Notice of Invitation to Apply<\/strong> – Date<\/li>\n
- Application Deadline<\/strong> – October 9, 2020<\/li>\n
- Scientific Review<\/strong> – October 2020 \u2013 November 2020<\/li>\n
- Awardees Notified<\/strong> – December 7, 2020<\/li>\n
- Just-in-Time Process<\/strong> – December 2020 – February 2021<\/li>\n
- Period of Performance<\/strong> – March 1, 2021 \u2013 February 28, 2022<\/li>\n<\/ul>\n
<\/div>[vc_empty_space height=”22px”][vc_column_text]ITHS is funded through a CTSA grant from NIH’s National Center for Advancing Translational Sciences (NCATS). NCATS requires the review and approval of all pilot grants involving human subjects research before funds are released. Therefore, if your proposal is awarded funding and involves human subjects research, additional documentation will be required. NCATS review and IRB review can be concurrent, but final NCATS approval is contingent upon IRB approval.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_accordion_tab][vc_accordion_tab title=”Frequently Asked Questions”][vc_column_text]<\/p>\n
FAQs<\/h5>\n
[\/vc_column_text][vc_column_text]
Translational Diabetes Research Award<\/h3>
Learn more about the Diabetes Research Center.<\/p><\/div><\/div>
Guidelines<\/h5>\n\n- Successful applications will address a critical knowledge gap in type 1 or type 2 diabetes and represents a key step toward improvement in the treatment or prevention of disease. The project must demonstrate significant scientific merit and provide a vision of how it could evolve to a more substantial body of work.Examples of projects that would be considered responsive to this RFA include (but are not limited to):\n
\n- Investigations into basic cellular processes involved in glucose metabolism or the regulation of insulin signaling with the use of in vitro<\/em> cell culture models or primary cells.<\/li>\n
- Animal studies with dietary, pharmacologic or genetic interventions to improve our understanding of glucose tolerance, insulin sensitivity, pancreatic b-cell function or diabetic complications.<\/li>\n
- Human observational or epidemiological studies to identify risk factors for type 1 or type 2 diabetes or complications of diabetes.<\/li>\n
- Randomized controlled trials of diet or other lifestyle interventions, investigational drugs or devices, or other interventions (e.g. bariatric surgery) to assess their impact on glycemic control, glucose tolerance or complications of diabetes.<\/li>\n<\/ul>\n<\/li>\n
- Plan to spend your money in 1 year. No-cost extensions will not be allowed. ITHS faculty or staff may be listed as active research contributors on a case-by-case basis. Please consult with ITHS prior to application submission if your proposal includes ITHS faculty or staff.<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Eligible Investigators”][vc_column_text]<\/p>\n
Eligible Investigators<\/h5>\n
Faculty members at ITHS Partner Institutions, including the University of Washington, Fred Hutch Cancer Research Center, Seattle Children\u2019s Research Institute, and other academic institutions affiliated with the ITHS in the WWAMI (Washington, Wyoming, Alaska, Montana, Idaho) region are eligible to apply for this pilot award. Collaborations may extend outside the WWAMI region; however, funds may not be transferred outside the United States. ITHS-funded faculty and staff are ineligible to apply. An acting faculty member or instructor is eligible to apply only if the Department head provides a letter supporting the applicant\u2019s eligibility to serve as PI.<\/p>\n
All Investigators on the research team must be ITHS Members in order to apply. To become a member, please complete the ITHS Membership Form<\/a>.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Application Process”][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_column_text]<\/p>\nApplication Process<\/h5>\n
[\/vc_column_text][vc_column_text el_class=”hide”]<\/p>\n
\n\n\nA. Letter of Intent<\/h6>\n
The letter of intent form must be submitted through the ITHS website before submission of the application. The form includes information on\u00a0the applicant and any Co-Investigators or Community Partners, project title, and abstract (250 word maximum). Investigators who are invited to submit a full application will receive notice within two weeks.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=”” el_class=”hide”][vc_column_inner][vc_empty_space height=”12px”]Submit a Letter of Intent<\/i><\/a>[\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_empty_space height=”12px”][vc_column_text]<\/p>\nA. Application<\/h6>\n
The application must be submitted through the ITHS website.<\/p>\n
Applications will follow National Institutes of Health (NIH) formatting guidelines (see FAQ) and include:<\/p>\n95 KB<\/span>1) Cover Page<\/a>\n2)<\/strong> Project Title and Abstract (250 word maximum)
\n3)<\/strong> Research Plan, 2-pages (references do not count toward page limit)<\/div>\n57 KB<\/span>4)\u00a0Project Timeline – 1-page<\/a>\n5)<\/strong>\u00a0Budget and Budget Justification<\/strong>\u00a029 KB<\/span>5a) Budget<\/a> 37 KB<\/span>5b) Budget Justification<\/a><\/div>\n6)<\/strong> Letter(s) of Support<\/strong> –\u00a0<\/strong>Letters of Support are not required unless you are an instructor or acting faculty member.\u00a0<\/strong>If you are an instructor or acting faculty member, you will need to\u00a0include a letter supporting your eligibility to serve as PI from your Department head (or equivalent).<\/div>\n35 KB<\/span>7) NIH format Biosketches for all investigators (senior\/key personnel)<\/a>[\/vc_column_text][vc_column_text][vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′]<\/p>\nNot included in the above document:<\/h6>\n
Suggested Reviewers<\/strong> –\u00a0You will also be asked to provide five suggested reviewers, including the following information for each: 1) Name, 2) Title, 3) Institution\/Organization, and \u00a04) Email Address.<\/p>\nA general note about conflict of interest:<\/em> A reviewer would have a conflict of interest if they are the applicant’s mentor, dept. chair, spouse, or close relative; or if they currently work together on manuscripts, grants, or business ventures. Simply being in the same department or division is not, in and of itself, a conflict of interest.
\n[vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′][\/vc_column_text][vc_empty_space height=”22px”]Apply Now<\/i><\/a>[vc_empty_space height=”22px”][vc_column_text]<\/p>\nB. Timeline<\/h6>\n
[\/vc_column_text]
<\/p>\n\n- Letter of Intent Deadline<\/strong> – Date<\/li>\n
- Notice of Invitation to Apply<\/strong> – Date<\/li>\n
- Application Deadline<\/strong> – October 9, 2020<\/li>\n
- Scientific Review<\/strong> – October 2020 \u2013 November 2020<\/li>\n
- Awardees Notified<\/strong> – December 7, 2020<\/li>\n
- Just-in-Time Process<\/strong> – December 2020 – February 2021<\/li>\n
- Period of Performance<\/strong> – March 1, 2021 \u2013 February 28, 2022<\/li>\n<\/ul>\n
<\/div>[vc_empty_space height=”22px”][vc_column_text]ITHS is funded through a CTSA grant from NIH’s National Center for Advancing Translational Sciences (NCATS). NCATS requires the review and approval of all pilot grants involving human subjects research before funds are released. Therefore, if your proposal is awarded funding and involves human subjects research, additional documentation will be required. NCATS review and IRB review can be concurrent, but final NCATS approval is contingent upon IRB approval.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_accordion_tab][vc_accordion_tab title=”Frequently Asked Questions”][vc_column_text]<\/p>\n
FAQs<\/h5>\n
[\/vc_column_text][vc_column_text]
Translational Diabetes Research Award<\/h3>
- \n
- Investigations into basic cellular processes involved in glucose metabolism or the regulation of insulin signaling with the use of in vitro<\/em> cell culture models or primary cells.<\/li>\n
- Animal studies with dietary, pharmacologic or genetic interventions to improve our understanding of glucose tolerance, insulin sensitivity, pancreatic b-cell function or diabetic complications.<\/li>\n
- Human observational or epidemiological studies to identify risk factors for type 1 or type 2 diabetes or complications of diabetes.<\/li>\n
- Randomized controlled trials of diet or other lifestyle interventions, investigational drugs or devices, or other interventions (e.g. bariatric surgery) to assess their impact on glycemic control, glucose tolerance or complications of diabetes.<\/li>\n<\/ul>\n<\/li>\n
- Plan to spend your money in 1 year. No-cost extensions will not be allowed. ITHS faculty or staff may be listed as active research contributors on a case-by-case basis. Please consult with ITHS prior to application submission if your proposal includes ITHS faculty or staff.<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Eligible Investigators”][vc_column_text]<\/p>\n
Eligible Investigators<\/h5>\n
Faculty members at ITHS Partner Institutions, including the University of Washington, Fred Hutch Cancer Research Center, Seattle Children\u2019s Research Institute, and other academic institutions affiliated with the ITHS in the WWAMI (Washington, Wyoming, Alaska, Montana, Idaho) region are eligible to apply for this pilot award. Collaborations may extend outside the WWAMI region; however, funds may not be transferred outside the United States. ITHS-funded faculty and staff are ineligible to apply. An acting faculty member or instructor is eligible to apply only if the Department head provides a letter supporting the applicant\u2019s eligibility to serve as PI.<\/p>\n
All Investigators on the research team must be ITHS Members in order to apply. To become a member, please complete the ITHS Membership Form<\/a>.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab title=”Application Process”][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_column_text]<\/p>\n
Application Process<\/h5>\n
[\/vc_column_text][vc_column_text el_class=”hide”]<\/p>\n
\n\n\nA. Letter of Intent<\/h6>\n
The letter of intent form must be submitted through the ITHS website before submission of the application. The form includes information on\u00a0the applicant and any Co-Investigators or Community Partners, project title, and abstract (250 word maximum). Investigators who are invited to submit a full application will receive notice within two weeks.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=”” el_class=”hide”][vc_column_inner][vc_empty_space height=”12px”]Submit a Letter of Intent<\/i><\/a>[\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=”row” type=”full_width” text_align=”left” css_animation=””][vc_column_inner][vc_empty_space height=”12px”][vc_column_text]<\/p>\n
A. Application<\/h6>\n
The application must be submitted through the ITHS website.<\/p>\n
Applications will follow National Institutes of Health (NIH) formatting guidelines (see FAQ) and include:<\/p>\n95 KB<\/span>1) Cover Page<\/a>\n
2)<\/strong> Project Title and Abstract (250 word maximum)
\n3)<\/strong> Research Plan, 2-pages (references do not count toward page limit)<\/div>\n57 KB<\/span>4)\u00a0Project Timeline – 1-page<\/a>\n5)<\/strong>\u00a0Budget and Budget Justification<\/strong>\u00a029 KB<\/span>5a) Budget<\/a> 37 KB<\/span>5b) Budget Justification<\/a><\/div>\n6)<\/strong> Letter(s) of Support<\/strong> –\u00a0<\/strong>Letters of Support are not required unless you are an instructor or acting faculty member.\u00a0<\/strong>If you are an instructor or acting faculty member, you will need to\u00a0include a letter supporting your eligibility to serve as PI from your Department head (or equivalent).<\/div>\n35 KB<\/span>7) NIH format Biosketches for all investigators (senior\/key personnel)<\/a>[\/vc_column_text][vc_column_text][vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′]<\/p>\n
Not included in the above document:<\/h6>\n
Suggested Reviewers<\/strong> –\u00a0You will also be asked to provide five suggested reviewers, including the following information for each: 1) Name, 2) Title, 3) Institution\/Organization, and \u00a04) Email Address.<\/p>\n
A general note about conflict of interest:<\/em> A reviewer would have a conflict of interest if they are the applicant’s mentor, dept. chair, spouse, or close relative; or if they currently work together on manuscripts, grants, or business ventures. Simply being in the same department or division is not, in and of itself, a conflict of interest.
\n[vc_separator type=’normal’ position=’center’ color=” thickness=’1′ up=’16’ down=’6′][\/vc_column_text][vc_empty_space height=”22px”]Apply Now<\/i><\/a>[vc_empty_space height=”22px”][vc_column_text]<\/p>\nB. Timeline<\/h6>\n
[\/vc_column_text]
<\/p>\n- \n
- Letter of Intent Deadline<\/strong> – Date<\/li>\n
- Notice of Invitation to Apply<\/strong> – Date<\/li>\n
- Application Deadline<\/strong> – October 9, 2020<\/li>\n
- Scientific Review<\/strong> – October 2020 \u2013 November 2020<\/li>\n
- Awardees Notified<\/strong> – December 7, 2020<\/li>\n
- Just-in-Time Process<\/strong> – December 2020 – February 2021<\/li>\n
- Period of Performance<\/strong> – March 1, 2021 \u2013 February 28, 2022<\/li>\n<\/ul>\n
<\/div>[vc_empty_space height=”22px”][vc_column_text]ITHS is funded through a CTSA grant from NIH’s National Center for Advancing Translational Sciences (NCATS). NCATS requires the review and approval of all pilot grants involving human subjects research before funds are released. Therefore, if your proposal is awarded funding and involves human subjects research, additional documentation will be required. NCATS review and IRB review can be concurrent, but final NCATS approval is contingent upon IRB approval.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_accordion_tab][vc_accordion_tab title=”Frequently Asked Questions”][vc_column_text]<\/p>\n
FAQs<\/h5>\n
[\/vc_column_text][vc_column_text]
Translational Diabetes Research Award<\/h3>
- Notice of Invitation to Apply<\/strong> – Date<\/li>\n