This study aims to evaluate the safety and effects of a study cream called ruxolitinib compared with a vehicle cream in individuals with Hidradenitis Suppurativa. The vehicle cream, which does not contain the active drug, will be used to help determine whether the study cream…
The purpose of this study is to understand how to help people with an ICD start or increase an exercise program. We also want to know if a home-based walking program will: increase the number of steps per day, boost confidence in being physically active,…
The purpose of the study is to better understand the effects and potential benefits of elamipretide on skeletal muscle and cognitive function in older adults. Elamipretide, the study drug, has FDA accelerated approval as Forzinity™ only for use in the treatment of patients with Barth...
This research study is studying to see if Silodosin in combination with Guanfacine could function as an effective, reversible, on demand male contraceptive. The purpose of this study is to test silodosin and guanfacine and understand the following: • How long does it take after...
The Brain Influences on growth at Birth Study is trying to learn how the baby brain and nutrition contributes to weight gain and growth early in life in babies of mothers who experienced gestational diabetes. We are recruiting pregnant individuals or families with babies up...
Study Description The purpose of this study is to evaluate the effect of tibulizumab in adults with Hidradenitis Suppurativa. Tibulizumab is an experimental drug, which means it has not been approved by the Food and Drug Administration (FDA). This means the safety and effectiveness of...
This study aims to understand how adults with an acquired brain injury think about their condition as part of who they are. We also want to know if certain factors and life experiences shape someone’s sense of identity. Ultimately, we want to identify ways to…
Participants will listen to a series of sentences and record what they hear. The study will take about an hour to complete. Location can be flexible To determine the effects of enhancement delay and intensity on speech intelligibility. To evaluate how delay impacts subjective sound…
This study is looking at how an investigational study drug, called teplizumab, might possibly help protect insulin-producing cells by affecting the immune cells that attack them. The main goal of the study is to see if teplizumab can work better than a placebo (a look-alike...
The purpose of this study is to assess the feasibility, acceptability, and effectiveness associated with Taking Action for college students with serious mental illnesses (SMI). The study will be a randomized controlled trial. We plan to recruit 300 college students with SMI to participate in...
