Brain & Nervous System

We want to know more about why people donate to medical crowdfunding campaigns, and how they decide which campaigns to donate to. Medical crowdfunding is a method for raising money for health needs by asking for small donations from many people on sites like GoFundMe….

This is a multicenter longitudinal study that aims to validate a set of measures that were previously identified as promising candidate biomarkers and/or sensitive and reliable objective measures of social function in ASD for potential use in clinical trials. The confirmation study will repeat the…

SPARK is a free, online study with a simple mission: to speed up research and advance the understanding of autism. SPARK study is now the largest autism research study in the world, with over 275,000 study participants. An important part of SPARK is the collection of…

The primary objective of this study is to assess the efficacy of botulinum toxin injections to the upper limb muscles for essential tremor. In the first part of the study, only one arm will be injected with either botulinum toxin or placebo and then followed…

Researchers at the UW Bloedel Hearing Research Center want to learn about how the brain helps us listen in noisy real-world environments. This study is for 7 to 10-year-old children and parents. If you decide to participate in this research study, you and your child…

Researchers at the UW Bloedel Hearing Research Center want to learn about how the brain helps us listen in noisy real-world environments. This study is for 4 to 18-year-old children and parents. If you decide to participate in this research study, you and your child...

People with multiple sclerosis (MS) often have problems with fatigue. For some people, fatigue is their most debilitating symptom of MS. Yet, many of the available treatments provide inadequate relief for fatigue. Past research has found that training in self-hypnosis is linked to reduced fatigue…

To evaluate the efficacy, safety, and tolerability of AVP-786 compared to placebo, for the treatment of agitation in patients with dementia of the Alzheimer's type To evaluate the effects of AVP-786 compared to placebo on neuropsychiatric symptoms To evaluate the effects of AVP-786 compared to…

To evaluate the clinical efficacy of ATH-1017 To determine the safety and tolerability of ATH-1017 To evaluate the clinical efficacy of ATH-1017 separately on: (1) cognition and (2) clinical global impression of change To evaluate the effect of ATH-1017 on activities of daily living To…

To assess the effect of donanemab versus placebo on clinical progression in participants with early symptomatic AD with demonstrated presence of tau pathology To assess the effect of donanemab versus placebo on clinical progression of participants with early symptomatic AD To assess the effect of…

The purpose of this study is to understand whether metformin (Glucophage® XR), a medication used for diabetes treatment and prevention, can prevent a decline in memory and thinking abilities for people who are already having mild memory problems. At the first study visit you would have…

BASIC2 is studying ways to help overweight kids and their parents reach and maintain a healthy weight. This longitudinal study is trying to learn if the study medicine combined with family-based treatment helps kids better manage their weight. You and your child would attend free…

The Cognition and Cortical Dynamics Laboratory at the University of Washington is recruiting healthy English-Chinese bilingual participants for a study that occurs over 7 weeks where individuals will be tested on a battery of language and cognitive measures, followed by 6 weeks of computer programming…

The purpose of this pilot study is to record the daily human activities, and to develop predictive models of physical activity. We hope this study will enable researchers to test and validate new technologies that may subsequently be used to study and inform researchers and…

Ambulatory children with cerebral palsy (CP) walk predominately in low intensity stride rates with little variability, thus limiting their walking activity and ability to participate in daily life. In contrast, typically developing (TD) children engage in short bursts of intense walking activity interspersed with varying…

Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively influence their ability to physically participate in day to day life. The investigators propose that impaired muscle power generation is the key limiting factor affecting walking activity and participation. This proposal represents a combined…

Ambulatory children with cerebral palsy (CP) demonstrate altered lower limb biomechanical alignment in walking (e.g. excessive hip/knee flexion or equinus during stance) and experience walking activity limitations that negatively influence their ability to participate in day to day life. Ankle Foot Orthoses (AFO) are a…

The University of Washington Institute for Language and Brain Sciences is recruiting hard of hearing infants between 2 and 12 months of age who have a mild-to-moderate hearing loss. This study looks at the effects of hearing loss on early brain development and learning. The…

The Infant Brain Imaging Study, or IBIS, is a research study of brain development in infants and children. The IBIS Network is a consortium of researchers across North America, including the University of Washington, that work together to discover early changes in brain development of…

The Infant Brain Imaging Study, or IBIS, is a research study of brain development in infants and children with autism. The IBIS Network is a consortium of researchers across North America, including the University of Washington Autism Center, that work together to discover early changes…

University of Washington researchers, led by Drs. Natalia Kleinhans and Stephen Dager, are recruiting pregnant participants who have not used marijuana during their first trimester and those who have used marijuana during their first trimester for a new study of prenatal development. Participants are not...

Study Description WEB study is a longitudinal study that will examine changes that may occur in the brain following obesity treatment. We are currently recruiting: People with BMI of 18.5-24.9 and who meet other study criteria People planning to have weight loss surgery with their…

Our team is the NeuDLL (Neurodevelopmental Disorders Language & Learning) Lab in the UW Speech & Hearing Department. We are seeking families to participate in research related to spoken language in children with and without developmental disorders. Our current study focuses on how children learn…

The purpose of this study is to identify possible brain or spinal cord differences in participants with ALS compared to participants without ALS. Research shows that 90 to 95 percent of ALS cases occur at random, with only 5-10 percent of ALS cases being inherited….

We are learning more and more about the risks for Alzheimer’s disease every year, and that includes learning what foods are best at promoting brain health. It might be more complicated than ‘this food is good or bad.’ Dr. Angela Hanson, a geriatric physician at…

The GET Smart study is looking at whether exercise has an impact on cognition in people with MS. Researchers at the University of Washington are studying exercise because other studies have shown that exercise can help cognition in other non-MS populations. However, currently we do…

This protocol includes studies of the control and coordination of speech production. Various hypotheses are being investigated in our laboratory with the common aim of improving our understanding of the processes and mechanisms underlying normal and disordered speech. The common procedure across these studies consists…