Bones, Joints & Muscles

Our research team would like to learn more about the needs and priorities of individuals and families affected by genetic conditions. The information we learn may help us understand what research topics are most valuable to families and most likely to be helpful in the…

The purpose of the study is to investigate the metabolic profiles of people with chronic low back pain and fibromyalgia. We are looking for individuals with chronic low back pain. Study participants will fill out a questionnaire about their medical history and demographic information before…

Chronic pain is a significant problem affecting millions of Americans. Research has shown that psychological treatments can help people with chronic pain manage their pain and improve their quality of life. Three psychological treatments shown to be effective for chronic pain include Mindfulness-Based Cognitive Therapy…

The EN 21-01 study is testing a new investigational medication, called NRD135S.E1, to see if it is helpful and safe for patients with painful diabetic peripheral neuropathy. NRD135S.E1 showed a decrease in pain after 3 weeks of study treatment when compared to a placebo in…

The Testosterone in Cancer Survivors study is a research study in men, ages 18-54, who have received chemotherapy and/or radiation therapy for their cancer and are now off-treatment and in remission for at least 1 year. The purpose of this study is to evaluate whether…

Arthritis is a common condition in the United States, and a leading cause of pain and disability. Physical exercise is recommended for managing arthritis, but access to evidence-based exercise programs is limited, particularly in rural areas. Therefore, the investigators propose to evaluate remote delivery of…

The main purpose of this study/trial is to test whether patients with HMGCR myopathy can be safely and effectively treated with IVIG as their only medication for this condition. Participant Eligibility Potential subjects must meet the following: – Have a positive Anti-HMGCR antibody lab result…

Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively influence their ability to physically participate in day to day life. The investigators propose that impaired muscle power generation is the key limiting factor affecting walking activity and participation. This proposal represents a combined…

Ambulatory children with cerebral palsy (CP) demonstrate altered lower limb biomechanical alignment in walking (e.g. excessive hip/knee flexion or equinus during stance) and experience walking activity limitations that negatively influence their ability to participate in day to day life. Ankle Foot Orthoses (AFO) are a…

The PACIFIC Study is testing whether group exercise in combination with education on aging and health or behavioral health improves pain and physical function in older adults with knee arthritis. Participant Eligibility 65 years or older Have a diagnosis of knee osteoarthritis Have knee pain…