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Allergies & Immune System

Allergies & Immune System

Participate in Research is designed to connect potential volunteers with open research studies. We are looking for volunteers just like you to help answer important questions about allergies and the immune system. This page lists studies that may apply to you or someone you know. If you find a study that you’d like to participate in, you can contact the study team with questions or to volunteer. Join us to improve the health of others.

Active Studies

Immunology studies of rheumatoid arthritis and cancer

The long-term goal of this research study is to learn more about the body’s immune system and how it can fight cancer or autoimmune diseases. This knowledge may help lead to the development of treatments that uses the body’s own defense system. We are looking…

Monoclonal antibodies for the prevention of symptomatic COVID-19 infection in individuals who are immunocompromised

This study’s primary objective is to evaluate the effect of casirivimab+imdevimab, compared with placebo, in preventing symptomatic SARS-CoV-2 infection in immunocompromised participants. The duration of the study for an individual participant is approximately 267 days, including up to 14 days of screening. There is a…

Would You Like to Donate Blood for a Study about Allergies and/or Asthma?

Asthma and allergies are very common health problems. Cells in the blood that are called “inflammatory cells” are involved in the development of asthma and/or allergies, but we do not know exactly how these cells are involved in asthma and/or allergies. In this research study,…

Immune Response in Asthma

Asthma is a condition where people experience symptoms of wheezing and shortness of breath in response to exposures such as allergens and exercise. There are many people who have allergies to substances in the environment such as pollen or grasses, but only some of the…

The VIVA Trial

The VIVA Clinical Trial (Vaccine to Interrupt Progression of Vulvar and Anal Neoplasia) will test whether the Human Papillomavirus (HPV) vaccine can improve the health of people who have been previously diagnosed with pre-cancerous lesions. We plan to enroll men and women in the Seattle…

TB and Mycobacterium avium complex (MAC) study

The purpose of this study is to understand why people have different susceptibility to infection, how the immune system fights infections, and differences between individual’s immune systems. We’re looking for people who have been diagnosed with tuberculosis or another Mycobacterium. Study procedures involve a blood…

Lung Responses to Infection

The airspaces of our lungs are guarded by alveolar macrophages, which are very specialized infection-fighting cells that ingest and kill most inhaled bacteria and release substances that control inflammatory responses in the lungs. However, there are some bacteria that are able to survive and replicate...

Blood and Lung Responses to Infection

The overall goal of this project is to study the inflammatory response of lung and blood cells to infection with Burkholderia pseudomallei. As a part of our study, we ask eligible individuals to undergo a blood draw and a bronchoscopy (a procedure to obtain cells…

Malaria Infection Screening for People Who Grew Up in Areas Where Malaria is Widespread

Malaria is a deadly disease that affects 300-500 million people every year. We hope to develop vaccines and medicines to prevent and limit malaria disease and deaths. The Seattle Malaria Clinical Trials Center is looking for volunteers to take part in an upcoming research study…

The CANNABIS Study: Impact of Cannabis on Inflammation and Viral Persistence in Treated HIV

Could cannabis help us treat HIV? Despite being undetectable, people living with HIV have ongoing inflammation, which is the body’s reaction to infection, a state where some of your immune cells remain constantly activated. As well, HIV damages the lining of your intestines soon after infection….

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