TrialNet is studying rezpegaldesleukin to see if it can help the body continue making insulin in people newly diagnosed with type 1 diabetes (TID) by stimulating regulatory T cells to restore immune balance. Rezpegaldesleukin is already being studied in people with other autoimmune diseases like…
This is a platelet transfusion study. The primary purpose of this study is to determine if Biotin (vitamin B7) is an effective way to label platelets in survival and recovery studies. This study involves using a radioactive material as well as Biotin added to your...
The MARITIME-CV Study is a Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants with Atherosclerotic Cardiovascular Disease and Overweight or Obesity This study is being done to learn if maridebart cafraglutide (MariTide) can reduce the...
Many people notice changes in their memory or thinking as they get older—like occasionally forgetting where they put their keys, struggling to find a word, or feeling less sharp than before. These experiences are called Subjective Cognitive Decline (SCD). How people understand, talk about, and...
The goal of this study is to conduct an initial open pilot trial of the online PTSD prevention/recovery promotion program CARE for sexual minority bias violence survivors and their supporters. CARE is a two-session intervention for violence survivors and their supporters (e.g., friends, family) that…
Study Description: Kaiser Research is inviting volunteers to join a research study of an investigational nasal spray vaccine against COVID-19 to help evaluate the vaccine’s safety, tolerability, and immune response. Enrollment may be ongoing for several months. Volunteers do not need to be Kaiser members....
This study aims to evaluate the safety and effects of a study cream called ruxolitinib compared with a vehicle cream in individuals with Hidradenitis Suppurativa. The vehicle cream, which does not contain the active drug, will be used to help determine whether the study cream…
The purpose of this study is to understand how to help people with an ICD start or increase an exercise program. We also want to know if a home-based walking program will: increase the number of steps per day, boost confidence in being physically active,…
The Brain Influences on growth at Birth Study is trying to learn how the baby brain and nutrition contributes to weight gain and growth early in life in babies of mothers who experienced gestational diabetes. We are recruiting pregnant individuals or families with babies up...
Study Description The purpose of this study is to evaluate the effect of tibulizumab in adults with Hidradenitis Suppurativa. Tibulizumab is an experimental drug, which means it has not been approved by the Food and Drug Administration (FDA). This means the safety and effectiveness of...