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Lung Responses to Infection

Lung Responses to Infection

The airspaces of our lungs are guarded by alveolar macrophages, which are very specialized infection-fighting cells that ingest and kill most inhaled bacteria and release substances that control inflammatory responses in the lungs. However, there are some bacteria that are able to survive and replicate within these alveolar macrophages. These organisms are known as intracellular pathogens. The goal of our research project is to discover why these bacteria are able to infect human alveolar macrophages and what makes alveolar macrophages susceptible to intracellular bacterial infection.

As a part of our study, we ask eligible individuals to undergo a blood draw and a bronchoscopy (a procedure to obtain cells from the lungs) at Harborview Medical Center.

Participants will be paid $150 for completing the study visit.

Participant Eligibility

— Between the ages of 18 and 50
— Generally healthy without any chronic medical conditions
— Non-smoker, or have abstained from smoking for at least three months prior to the study visit
— No allergy to lidocaine
— Not on any prescription medication other than birth control
— No vaccinations within the last six weeks
— No recent upper respiratory infection (cold or flu) or antibiotic use within the last 4 weeks
— Not pregnant

Contact

Denise
(206) 637-2585

Additional Study Details

Full Study Title
Lung and Blood Responses to Intracellular Infection

Study ID: STUDY00004670
Start Date: 04/09/2018
End Date: 04/30/2020

Investigator(s)
Dr. Shawn Skerrett, M.D., F.A.C.P., F.C.C.P

Accepts Healthy Volunteers?
Yes

Study Site(s)

Harborview Medical Center

300 9th AVE
Seattle, Washington 98104



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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