Quick Links

Substance Use and Elevated Blood Pressure in the Lungs

Substance Use and Elevated Blood Pressure in the Lungs

The purpose of this study is to determine if the use of alcohol, tobacco, marijuana, pain medications, and other substances is associated with elevated blood pressure in the lungs (pulmonary arterial hypertension (PAH)).

We are looking for healthy controls to compare their information to people with elevated blood pressure in the lungs.

The Study consists of a one time visit, lasting approximately 1 hour. During that visit, researchers will collect urine and less than 4 tablespoons of blood for research purposes. Participants will be asked to fill out a computer-based questionnaire about current and past tobacco, alcohol, and drug use.

Participants will receive a $50 virtual gift card after completing the study visit.

Participant Eligibility

Inclusion Criteria
• Able to provide Informed consent
• Able to understand and speak English

Exclusion Criteria
• History of heart disease, including any cardiac procedure (catheterization etc.).
• History of lung disease, such as chronic obstructive pulmonary disease or interstitial lung disease
• History of sleep apnea, for which nocturnal ventilation has been recommended
• Medical comorbidities which can be associated with PAH, including connective tissue disease, congenital heart disease, cirrhosis/portal hypertension and HIV infection.
• Age < 18


Nancy Liston, MPH
(206) 221-6913

Additional Study Details

Full Study Title
Exposure to Substances in PAH: XPose PAH

Study ID: STUDY00016046
Start Date: 09/22/2022
End Date: 09/22/2027

Peter Leary, MD, PhD

Accepts Healthy Volunteers?

Study Site(s)

University of Washington- Montlake

1959 NE Pacific St.
Seattle, Washington 98195


Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.