The Seattle Children’s Research Institute (SCRI) – Center for Clinical Translational Research (CCTR) – Pediatric Clinical Research Center (PCRC) is a core resource within the Institute of Translational Health Sciences (ITHS) Clinical Research Center Network.
The Pediatric Clinical Research Center (PCRC) at Seattle Children’s provides an environment and resources for the multidisciplinary conduct of clinical research in children less than 21 years of age. The facility enables the study of a broad spectrum of human pathophysiology and diseases as well as commonly encountered clinical disorders. In addition to providing outpatient services, PCRC nurses can conduct research activities in other hospital areas including inpatient units, ER, OR, and ambulatory clinics.
Our Expertise
Our Expertise
PCRC research nurses are trained in Good Clinical Practice for Research and are PALS-certified. A primary nurse, assigned to each study, serves as the main point of contact. The primary nurse also develops the CRC protocol notebook (the standard reference guide for implementing your study in the PCRC) and conducts the protocol implementation meeting (PIM).
Who can use the PCRC?
Who can use the PCRC?
We require Seattle Children’s IRB approval for all studies. All investigators must be a credentialed Seattle Children’s provider or collaborate with a credentialed investigator.
The PCRC has many active studies from a broad range of departments/specialties including: Anesthesiology, Adolescent Medicine, Cardiology, Craniofacial, Critical/intensive Care, Emergency, Endocrinology, Gastroenterology, General Pediatrics, Genetics & Developmental Medicine, Hematology/oncology, Infectious Disease/immunology/Rheumatology, Nephrology, Pulmonary, Psychiatry and Behavioral Sciences, Rehabilitation Medicine/Occupational Therapy/Prosthetics and Orthotics, General Surgery, Biobehavioral Nursing and Health Systems, Human Health and Community Medicine-Epidemiology, Social Work.
Services
Services
The PCRC is located on the 8th floor of the Ambulatory Care Building (ACB) at Seattle Children’s Hospital.
| Facility Type | Total | Usage Notes |
|---|---|---|
| Dedicated outpatient exam rooms | 8 | All rooms have blood draw chairs, bed, Vital sign monitors, TV, VCR, DVD players |
| Sleep Study room | 1 | Includes video-taping equipment |
| Psychological and neuropsychological testing room | 1 | Includes video-taping equipment |
| Weights/Measurements Room | 1 | Stand up scale for wheelchair use, infant scales, Stadiometer, infant length boards, vital sign monitors, blanket warmer |
| Nourishment room | 1 | Provide snacks and drinks for research participants |
| Secured Medication room | 1 | |
| Drop in Computer workstations for study teams | 3 | 4 computers and telephones |
| Conference room | 1 | Seats 20, includes computer and overhead projector |
Procedures
Procedures
PCRC Medical Assistant
The PCRC Medical Assistant (MA) is trained to perform the following procedures.
- Assist the RN in any protocol related procedures
- Blood Draws
- EKGs
- Height, Weight, Head Circumference
- Specimen Collection: Nails, Saliva, Sputum, Stool, Urine
- Vital Signs/Pulse Oximetry
PCRC Nurses
The PCRC nurses are trained to perform the following procedures.
- Allergy skin testing
- Anaphylaxis monitoring and treatment
- Assistance with infant pulmonary function testing
- Assistance with concomitant medication and adverse event collection as allowed per protocol
- Anthropometrics/Body measurements
- Blood Draws
- Central venous catheter access
- EKG’s
- Glucose tolerance testing
- Infusion of investigational agents
- Intensive/Complex PK-PD collections
- Intravenous Line Placement (IVs)
- Lab specimen processing and short term storage
- Medication distribution
- Nasogastric Tube Placement (NGs)
- Nasal Swabs/Throat Swabs/Buccal Swabs for specimen collection or culture
- Pain assessments
- Patient monitoring
- PK studies
- Plasma/Serum Storage
- PO, SQ, Topical, IM, and IV medication administration
- PPD Placement and reading
- Questionnaire administration, interviews, and surveys
- Specimen Collection: Nails, Saliva, Sputum, Stool
- Spirometry
- Subject education
- Urine collection, storage
- Urine pregnancy testing
- Vital sings including oximetry
- Will train in any nursing approved protocol procedures
Equipment & Supplies
Equipment & Supplies
- BIA Analyzer System Quantum X
- Biodynamics-Body composition analyzer
- Blanket warmers
- Digital scales (infant and adult)
- Twelve-Lead EKG Machine with ability to download EKG’s
- Glucose monitoring (Roche AccuChek)
- Grason-Stadler Auto Tymp for tympanomometry
- Hydraulic Hand Dynamometer
- Infusion pumps
- Length Board
- Medication refrigerator
- Hospital beds ordered from central supply for sleep room
- Oxygen and suction in each room
- Oxygen, free standing mobile tank
- Oximeter
- Projector and Projector Screen
- In-floor scale (calibrated quarterly)
- Spirometer
- Stadiometer (calibrated weekly)
- TV/VCR/DVD in each exam room
- 4 Cameras/Video equipment, Mixer Splitter, DVD/VHS Recorder/Player, microphone
- Welch Allyn Vital Sign Monitors in each exam room
- EndoPAT Machine with computer software
Getting Started
Getting Started
Please complete the PCRC Application.
Contact Us
Contact Us
Related Links
Research Coordinator Core at Seattle Children’s
The Seattle Children’s Research Coordinator Core is a team of experienced clinical research staff available to collaborate with investigators and their research teams in all phases of clinical research. Staff possess expertise in protocol management, study implementation, and study coordination, and are well-versed in federal regulations, good clinical practice (GCP), and Seattle Children’s institutional requirements and policies.
To request services, please complete the online request form, or visit the Seattle Children’s website to learn more.