Translation: The process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public.
Translational Science: The field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process.
Source: Definitions provided by the National Center for Advancing Translational Sciences
Translational research includes:
- the process of making discoveries in the research laboratory or in preclinical studies that will have an impact on human health and may lead to the development of studies in humans,
- the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans and
- research aimed at enhancing the adoption of best practices in the community. Cost-effectiveness of prevention and treatment strategies is also an important part of translational science.
Source: Based on Institutional Clinical and Translational Science Award (U54) RFA-RM-07-007 CTSA RFA
Using this definition in our review and funding programs, the translational potential of research is rated as: