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Updated TL1 Offering: Unique Funding Opportunity for Pre-Doctoral Researchers

Updated TL1 Offering: Unique Funding Opportunity for Pre-Doctoral Researchers

The National Institutes of Health (NIH) is offering a unique funding opportunity for students interested in basic or patient-oriented research related to conditions that co-occur with Down syndrome, linked to awards held by ITHS.

New: Predoctoral students at the University of Washington and Montana State University who meet T32/TL1 eligibility criteria can request 2 years of support for stipend and tuition.

The INCLUDE initiative seeks to improve the health and well-being of individuals with Down Syndrome by better understanding risk and resilience factors for co-occurring conditions such as cognitive decline, cancers, and autoimmune disorders. Priorities include targeted, high-risk, high-reward basic research on chromosome 21 as well as patient-oriented research. In addition to funding, successful candidates will gain additional cross-disciplinary mentoring and training in translational science by joining dynamic peer cohorts supported by ITHS.

Wondering if your research project could be a fit? NIH has funded both basic research as well as patient-focused projects.

Funded projects have used mouse, human cell culture, and other models of Down Syndrome to study:

  • Protein synthesis dysregulation in cognitive decline
  • Role of polyamines in Alzheimer’s
  • RNA degradation in induced pluripotent stem cells
  • Autophagy deficits in clonal hematopoiesis linked to leukemia
  • Susceptibility genes for congenital heart defects
  • Immune dysregulation in human tissues

And has funded patient-focused research:

  • Epidemiology and social determinants of sleep apnea, dementia, and mortality
  • Brain behavior trajectories/development profiles from infancy through school-age

See full NIH funding announcement for details: NOT-TR-24-017

Interested in applying? Set up a meeting with us to discuss a potential research project or to learn more about the application process.

Submit your expression of interest by July 29th at 5 pm PT.

ITHS will help candidates develop full supplement applications to NIH in autumn of 2024. Eligibility and funding details can be found in the EOI form:

79 KB2024 Expression of Interest Form – NIH INCLUDE Admin Supplement (Reissue)

Please note, the ITHS general TL1 request for applications will open in autumn of 2024.